该程序的设计方式使学生在微生物学的各个领域都获得了强大的理论和实践知识。 The programme includes details of microorganisms of general, agricultural, industrial and medical importance, their metabolism, instrumentation and analytical techniques, molecular biology, biochemistry of microorganisms, nucleic acids, lipids, proteins & enzymes, immunology, genetic engineering, bioethics followed by applied biotechnology to make the study of living system more comprehensive with微生物学的深刻知识。实用课程旨在为学生提供微生物学方面的实验室技能。学生将能够设计和进行实验,并以有用形式进行分析和解释科学数据。该计划将为学生提供知识和技能基础,使他们能够在一般微生物学/农业/医学微生物学/生物技术/工业微生物学/食品微生物学/分子生物学及相关领域或涉及微生物学的多学科领域的高级研究。学生将获得微生物 /生物技术科学的广泛职业。学生将获得领域知识和知识,以实现学术界,行业和研究成功的职业生涯。最终目标是开发训练有素的人力资源,以协同的方式为社会的可持续发展开展工作。
Dual Therapy in Duodenal Ulcer Disease In Well controlled, double-blind studies, H. pylori infected duodenal ulcer patients received eradication therapy with clarithromycin 500 mg TID and omeprazole 40 mg daily for 14 days followed by omeprazole 40 mg (study A) or omeprazole 20 mg (studies B, C and D) daily for an additional 14 days;每个对照组的患者仅接受奥美拉唑单独接受28天。在研究A中,幽门螺杆菌在接受克拉霉素和奥美拉唑的80%的患者中被消除,仅1%的患者仅接受奥美拉唑。在研究B,C和D中,接受克拉霉素和奥美拉唑的患者的合并根除率超过70%,仅接受奥美拉唑的患者少于1%。在每项研究中,与单独接受奥美拉唑的患者相比,克拉霉素和奥美拉唑治疗的患者在6个月的溃疡复发率在统计学上较低。
越来越清楚的是,人类微生物群(也称为“隐藏器官”)在维持宿主的生理功能的许多过程中具有关键作用,例如营养萃取,生物活性分子的生物合成,与免疫,内分泌和势能与抗药性相互作用,以及与抗药性相互作用,以及抗癌症的抗性。In the last decade, the development of metagenomic approaches based on the sequencing of the bacterial 16s rRNA gene via Next Generation Sequencing, followed by whole genome sequencing via third generation sequencing technologies, has been one of the great advances in molecular biology, allowing a better pro fi ling of the human microbiota composition and, hence, a deeper understanding of the importance of microbiota in the不同病理学的疗法发生。在这种情况下,为疾病发病机理的人类微生物群的全面表征,以通过操纵微生物群来制定新的潜在治疗或预防策略至关重要。因此,这种观点将集中于微生物组实行和分析的当前和未来技术方法的进度,挑战和承诺。
中国有弹性城市报告将建筑有弹性城市的全球框架和ICELE经验综合,对中国城市进行的实践分析以及如何在中国建造弹性城市的探索,重点是“气候弹性”。In partnership with United Nations Office for Disaster Risk Reduction (UNDRR) and other distinguished actors, during year 2019 to 2021, ICLEI East Asia Secretariat closely worked with four project cities in China, to implement a series of training workshops promoting the ‘Making Cities Resilient' Campaign (followed by the ‘Making Cities Resilient 2030' initiative since 2021).培训研讨会植根于中国围绕城市灾害风险和应急管理的实际工作,涵盖了气候变化,缓解气候缓解和适应,气候投资和融资以及基于自然的解决方案等主题。MCR2030支持城市评估其当前的弹性水平,为改进设定目标以及实施策略以通过降低风险,适应和能力建设等各种行动来增强其韧性。
摘要 - 当今的商业格局的特点是竞争和动态,这将人力资源管理转变为组织的基本战略合作伙伴。员工营业额会带来影响生产力和知识管理的风险。本研究的重点是使用机器学习(ML)模型来预测员工的离职。在培训过程中,使用了一个由4410个记录和29个变量组成的数据集,在培训和评估十种模型的过程中,遵循了人工智能(AI)方法。调查结果表明,XG增强分类器(XGBC)和随机森林(RF)模型达到了最佳准确性和性能率,为98.8%和98.7%。Followed by Decision Tree Classifier (DT) with 97.6%, and the other models, such as Gradient Boosting Classifier (GBC), Ada boost Classifier (AC), Logistic Regression (LR), KN Classifier (K-NNC), SGD Classifier (SGDC), Support Vector Classifier (SVC) and Nu Support Vector Classifier (NuSVC), achieved the following费率:分别为88.4%,85.4%,84%,82.2%,83.0%,83.0%,55.0%。最后,可以得出结论,模型在预测中是有用且有效的。建议在人力资源管理策略中实施实际实施,以进行主动干预。
摘要。研究了pyogenes孤立培养的益生菌制剂的抗菌活性的结果,已经发现益生菌制剂Inoprovet2由BAC.Subtilis,BAC制备。licheniformis具有最早和最高的活性(从6小时开始,链球菌培养的减少39±0.9,24小时后 - 78±2.6,96小时后 - 100% - 即与其他人相比,破坏了脓液微生物)。Inoprovet1 differed from Inoprovet2 only by the quality of the excipient, but its activity was slightly lower (6 hours - 22 ±1.1, 24 hours - 53 ±3.9 and 96 hours - 100%), the third most active was Vitasporin12B probiotic (6 hours - 21 ±1.8, 24 hours - 51 ±2.3 and 96 hours - 98 hours - 98 ±4.2%), followed by Vetom 1。2(6小时后16±2.9,24小时后51±0.5,96小时后96±1.8%)和益生菌孢子蛋白,在6小时16±2.9,24小时后45±3.3和96小时89±2.6%后杀死链球菌培养的抗菌活性。获得的结果,在临床实践中使用inoprovet2益生菌的可能性不仅用于治疗胃肠道感染,而且还用于伤口感染
Test cells shall be secured to the testing machine by means of a rigid mount which will support all mounting surfaces of each test cell.Each cell or battery shall be subjected to a half-sine shock of peak acceleration of 150 gn and pulse duration of 6 milliseconds.Alternatively, large cells may be subjected to a half-sine shock of peak acceleration of 50 gn and pulse duration of 11 milliseconds.Each cell shall be subjected to three shocks in the positive direction followed by three shocks in the negative direction of three mutually perpendicular mounting positions of the cell or battery for a total of 18 shocks./ 以稳固的托架固定住每个样品。对每个电芯 样品以峰值为 150gn 的半正弦的加速度撞击,脉冲持 续 6ms ,另外,大电芯须经受最大加速度 50gn 和脉 冲持续时间 11ms 的半正弦波冲击,每个样品必须在 三个互相垂直的电池安装方位的正方向经受三次冲 击,接着在反方向经受三次冲击,总共经受 18 次冲 击。
结果:总共包括涉及1,321例患者的24项研究。There was an increased likelihood of wound healing with peripheral blood-derived stem cells, the most effective cells (odds ratios (OR) = 7.31, 95% CI: 2.90 – 18.47), followed by adipose-derived stem cells (OR = 5.23, 95% CI: 2.76 – 9.90), umbilical cord- derived stem cells (OR = 4.94, 95% CI: 0.61 - 40.03),骨衍生的干细胞(OR = 4.36,95%CI:2.43 - 7.85)和其他来源干细胞(OR = 3.16,95%CI:1.83 - 5.45)。然而,只有脐带衍生的干细胞显示出统计学意义(p <0.05)。异质性范围从脂肪和外周血组的不存在(I 2 = 0.00%)到骨骼组中等(I 2 = 26.31%)和其他组(I 2 = 30.62%),以及脐带组中的实质性(I 2 = 88.37%)。不对称的漏斗图指向出版偏差,但是对此进行纠正的修剪和填充方法使效应估计值较低:基于合并或校正或为3.40(95%CI 2.39 - 4.84)。干细胞疗法也与几个次要结果的改善有关,这表明它可能影响DFU的进展。
Figure 5 (Color online) (a) CLSM images of HepG-2 cells after incubation with TBPCP and TBCP (5 μM) under hypoxic conditions and two-photon irradiation (940 nm, 50 mW, 2 min) followed by staining with C11-BODIPY 581/591, Hoechst 33342, and Fer-1.对于C11-Bodipy 581/591:λEX= 561 nm; λEM= 570–620 nm。用于氧化的C11-Bodipy 581/591,λEX= 488 nm,λem= 500–530 nm。比例尺:10μm。(b)在深色和白光照射下用TBPCP和TBCP(5μM)处理的HEPG-2细胞的GSH水平(400-700 nm,200 mW/cm 2,10 min)。(c)在不同TBPCP处理的条件下,HEPG-2细胞中GPX4表达和GPX4的相对表达的蛋白质印迹分析。(d)在不同TBCP处理的条件下,HEPG-2细胞中GPX4表达和GPX4的相对表达的蛋白质印迹分析。误差线代表平均值±SD(每组n = 3), * p <0.05,** p <0.01,*** p <0.001。(e)TBPCP和TBCP处理的线粒体和核形态的生物-TEM(5μM)HEPG-2细胞在不同的处理后,比例尺:500 nm:500 nm。
•截至2021年6月11日,制造商已将333 678 903 COVID-1903 COVID-1903疫苗剂量分配给欧盟/欧洲经济区(EU/EEA)国家,其中包括上周超过3900万。Comirnaty (BNT162b2), developed by BioNTech/Pfizer, represents 67.3% of all doses distributed to EU/EEA countries via the European Commission's Vaccine Strategy, followed by Vaxzevria (AZD1222), previously called COVID-19 Vaccine AstraZeneca (19.5%), COVID-19 Vaccine Moderna (9.6%), and COVID-19-Janssen疫苗(3.3%)。•总共284 124 689疫苗剂量已在欧盟/EEA中服用,其中包括上周超过2500万。根据29个国家/地区的可用数据,自推出以来,已经在欧盟/EEA分配的剂量中有85%已经管理。•自2020年12月在欧盟/EEA的Covid-19疫苗部署开始以来,欧盟/EEA的成年人口(18岁以上)的累积疫苗接种已进展,至少达到51.2%,至少达到一个疫苗剂量(范围:14.9.9-9.7%)和26.7%的范围:(范围5)。 (30个报告国家)。•自疫苗推出以来,累积疫苗的摄取量较高,尤其是老年人和医护人员(HCW)。