Manasi

Nan Hua，博士-Weizhou Zhang实验室 Seyedehalaleh（Alaleh）Anvar -Weizhou Zhang实验室

1。Sajid Khan, Janet Wiegand, Peiyi Zhang, Wanyi Hu, Dinesh Thummuri, Vivekananda Budamagunta, Nan Hua , Lingtao Jin, Carmen J Allegra, Scott E Kopetz, Maria Zajac-Kaye, Frederic J Kaye, Guangrong Zheng, Daohong.bcl- XL Protac DEGRADER DT2216与Sotorasib在KRAS G12C突变癌症的临床前模型中协同作用。PMID：35260176 2。Dongwen Lv, Pratik Pal, Xingui Liu, Yannan Jia, Dinesh Thummuri, Peiyi Zhang, Wanyi Hu, Jing Pei, Qi Zhang, Shuo Zhou, Sajid Khan, Xuan Zhang, Nan Hua , Qingping Yang, Sebastian Arango, Weizhou Zhang, Digant Nayak, Shaun K Olsen，Susan T Weintraub，Robert Hromas，Marina Konopleva，Yaxia Yuan，Guangrong Zheng，Daohong Zhou。开发具有改善抗白血病活性的BCL-XL和BCL-2双降解器。PMID：34824248 3。Pratik Pal，Dinesh Thummuri，Dongwen LV，Xingui liu，Peiyi Zhang，Wanyi Hu，Saikat K Poddar，Nan Hua，Sajid Khan，Yaxia Khan，Yaxia Yuan，Yaxia Yuan，Xuan Zhang，Xuan Zhang，Daohong Zhun Zhoun Zhoung，Guangangong Zheng。发现具有增强BCl-2抑制作用的新型Bcl-XL Protac降解器。PMID：34533954 4。Xu -Xu Zhuang，Xuan Zang，Zheng，Nan Hua，Yi Sun，Yu -Hui Hu，Ling He。聚丙醇减轻APP/PS1小鼠中的认知功能障碍和神经病理学。pmid：29468792 5。Xuan Zang，Zhao-Yan Cheng，Yi Sun，Nan Hua，Li-Hua Zhu，Ling He。多巴胺D1样受体激动剂SKF38393对Aβ1-42诱导的认知障碍的改善作用和潜在机制。PMID：28939187 6。Xuan Zang，Zhao-Yan Cheng，Yi Sun，Nan Hua，Li-Hua Zhu，Ling He。PMID：28939187 7。PMID：25858697 8。9。多巴胺D1样受体激动剂SKF38393对Aβ1-42诱导的认知障碍的改善作用和潜在机制。Yu-hang锣，Nan Hua，Xuan Zang，Tao Huang，Ling He。褪黑激素可以改善小鼠模型中Aβ1-42诱导的阿尔茨海默氏症的认知缺陷。Madison E Carelock，Rohan P Master，Myung-Chul Kim，Zeng Jin，Lei Wang，Chandra K Maharjan，Nan Hua，Umasankar de，Ryan Kolb，Yufeng Xiao，Yufeng Xiao，Daiqing Liao，Guangrong Zheng Zheng Zheng，Weizhou Zhun。针对癌症免疫疗法的细胞类型特异性功能靶向细胞内蛋白。Sajid Khan, Patrick Kellish, Nick Connis, Dinesh Thummuri, Janet Wiegand, Peiyi Zhang, Xuan Zhang, Vivekananda Budamagunta, Nan Hua , Yang Yang, Umasankar De, Lingtao Jin, Weizhou Zhang, Guangrong Zheng, Robert Hromas, Christine Hann, Maria Zajac-kaye，Frederic J Kaye，Daohong Zhou。与DT2216和AZD8055共同靶向BCl-XL和MCL-1，可以协同抑制小细胞肺癌的生长，而不会引起小鼠的靶向毒性。PMID：36588105。10。Jing Pei, Yufeng Xiao, Xingui Liu, Wanyi Hu, Amin Sobh, Yaxia Yuan, Shuo Zhou, Nan Hua , Samuel G Mackintosh, Xuan Zhang, Kari B Basso, Manasi Kamat, Qingping Yang, Jonathan D Licht, Guangrong Zheng, Daohong Zhou, Dongwen LV。哌拉金偶联物诱导靶向蛋白质降解。PMID：36750097。