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Silicon Crossroads Microelectronics Commons
FOR IMMEDIATE RELEASE Silicon Crossroads Microelectronics Commons Marks Milestone Year CRANE, Ind. – As 2024 comes to a close, the Silicon Crossroads Microelectronics Commons (SCMC) Hub has emerged as a powerful catalyst for innovation and growth in the Midwest's microelectronics ecosystem. Under the leadership of Applied Research Institute (ARI), the hub has made substantial strides in fostering collaboration, driving technological advancements, and nurturing talent. SCMC is poised to help shape the future of microelectronics, strengthening America's global competitiveness and driving economic and national security. In its first year, SCMC focused on standing up its internal operations, and established a robust and diverse membership base spanning academia, small businesses, industry leading commercial companies and defense industrial base system integrators. This vibrant community was integral to driving ideation, advancing technologies through prototyping, and positioning projects for efficient transition to production. SCMC innovation processes and framework has made significant strides to accelerate microelectronics technology advancements through the proven innovation architecture. The nucleus of this framework incorporates collaborative ideation sessions, networking collisions, innovation templates/best practices, and the convergence of project teams. For example, SCMC's collaborative ideation sessions, such as the one held in June 2024, are designed to reduce innovation barriers. SCMC implemented a suite of tools, revolutionizing the operational capabilities. With these tools, the SCMC Hub can communicate efficiently, ensuring clear and timely information exchange among all members. This improved communication has resulted in better teaming opportunities, enabling more cohesive and strategic collaborations. The online member engagement platform houses all hub engagement, outreach, communications, event calendar, teaming profiles, member resources, data calls, and membership data. By utilizing this platform, SCMC members can interact with other hub members, receive pertinent Hub communications, partner with new innovative companies, share noteworthy news/articles, view announcements, and explore upcoming events. Upon the launch of this platform, our membership base consisted of 136 members, but saw significant and constant growth each quarter, bringing us to over 250 members, an 83% increase. Members can utilize the newly opened Silicon Crossroads Collaboration Center (SC3), which serves as a state-of-the-art hub for the SCMC, providing a modern and flexible space to foster collaboration, innovation, and knowledge sharing among the hub's diverse membership. The center's modular design accommodates a variety of events, workshops, and meetings, and already hosted over 36 activities that brought in more than 800 members and ecosystem partners. As a central gathering place for the three-state hub coalition, the SC3 plays a vital role in enabling the rich engagement and community-building that are critical to the hub's success. One of the most notable in 2024 was the establishment of the R1 Nucleus (R1N), an unprecedented collaboration between four prestigious regional universities: Purdue University, University of Notre Dame, University of Michigan, and University of Illinois Champaign- Urbana.
2024-未来-STEM-劳动力-GMiS-FINAL-240607.pdf
Ivy Tech 还与印第安纳州高等教育委员会密切合作，开展了“下一阶段学习途径”（NLPS）计划和“硅谷十字路口微电子公共区”（SCMC）项目等计划，旨在将学生教育重点放在行业需求上，并改善印第安纳州的 STEM 就业。这些合作包括与著名制造公司（如 John Deere）合作开展沉浸式学徒计划。此外，NLPS 计划还与 4 年制院校（尤其是普渡大学）合作，为 Ivy Tech 学生提供各种可叠加的认证和转学途径。这使学生拥有多种选择，可以根据自己的兴趣和目标个性化自己的教育途径，为他们进入职场做好最佳准备。
国家核安全局 Honeywell FM&T ...
目标 6 中还指出，FM&T 领导层缺乏对成本估算实践、采购和生产执行预测的明确监督，这对计划进度和库存系统计划的成本产生了重大影响。本报告期内，目标 2、3、4 和 5 的绩效成就显著。一些值得注意的成就包括按时向 NNSA 交付超过 1,730 套生产质量套件和 100 套培训和评估套件，以支持萨凡纳河核解决方案 (SRNS) 的升级活动（目标 2）；向其他政府机构和核武器可报销客户交付约 73,000 件物品，占计划交付量的 99%（目标 3）；开发和部署定制涂层系统（目标 4）；完成 23 号楼的租户改进和入住项目（目标 5）；以及供应链管理中心 (SCMC) 的有效运行，从而实现 4.153 亿美元的战略节约（目标 6）。
使用SCOR评估供应链性能（供应...
＃信息系统部，UIN Sunan Ampel Surabaya JL。艾哈迈德·亚尼（Ahmad Yani）117号，杰穆尔·沃萨里（Jemur Wonosari），凯克（Kec）。wonocolo，East Java的Surabaya，East Java电子邮件： * 1 bimbing20@gmail.com，2 andik@uinsby.ac.id，3 yusuf.amrozi@uins.ac.ac.id摘要商业竞赛，该竞赛使每个公司都汇编了一项新的策略，以在竞争中取得领先地位。商业竞赛在于公司如何应用产品的过程以及与其他业务竞争对手的更便宜，更高质量和更快的服务。因此，我们需要对与公司绩效相关的所有方面进行全面评估和测量。评估简历上的供应链性能。XYZ使用供应链操作参考模型（SCOR 11.0）。根据可靠性，响应能力，成本和资产属性来确定工业策略的活动，然后使用1级矩阵测量，因为标准绩效过程的测量使用了1级矩阵。使用CV上的11.0 SCOR模型进行的计算。XYZ在2019年，POF的结果（完美订单全额）为89.33％，OFCT（周期全额满足订单）20-21天，COGS（现金出售的现金）为67.62％，SCMC（供应链管理成本）为67.30％。关键字：供应链操作参考（SCOR），支持链管理，对抽象绩效激烈的业务竞争的评估使每个公司都制定了一种新的策略，以在竞争中取得领先。评估CV的供应链性能。商业竞争在于公司如何应用与其他业务竞争对手更便宜，更高质量和更快的产品和服务的过程。因此，需要对与公司绩效相关的所有方面进行全面评估和测量。XYZ使用供应链操作参考（SCOR 11.0）模型。根据可靠性，响应，成本和资产的属性来确定工业策略的活动，然后使用1级矩阵测量，因为过程性能标准的测量使用了1级矩阵。使用CV上的SCOR 11.0模型进行计算。XYZ在2019年，从POF（完美订单全额）获得的结果为89,33％，OFCT（订单全填充周期时间）20-21天，COGS（售价的现金）为67,62％，SCMC（供应链管理成本）为67,30％。关键字：供应链操作参考，供应链管理，评估测量
细胞骨架成分的先天突变引起DNA dna甲基化...
uhrf1在受精后主要迁移到卵和胚胎中的细胞质，其中少量的UHRF1在某些区域（例如ICR）中维持甲基化修饰的细胞核中剩余少量。另一方面，除了受精后立即卵和胚胎外，所有UHRF1均易位到细胞核中，并在与细胞分裂相关的DNA复制过程中复制甲基化修饰。由于使用卵的实验受到局限性，因此研究小组使用人类培养的细胞发现NLRP5和OOEEP与构成SCMC的核心蛋白之间的结合。研究小组还产生了一条细胞系，可以通过药物诱导的诱导UHRF1（称为Cuhrf1：图1），该细胞系已被修饰以将其定位为细胞质，就像卵子一样，并检查了Cuhrf1在NLRP5和OOEP存在下CuHRF1变化的蛋白质稳定性。我们发现，在OOEEP存在下，CuHRF1的稳定性不会改变，但是在NLRP5存在下，Cuhrf1的稳定性增加了两倍以上（图2）。我们还发现，NLRP5缺陷小鼠的卵中的细胞质和细胞核中UHRF1蛋白的量均降低。该结果表明，在易位进入细胞核后，稳定的UHRF1的一部分可能稳定存在。