Artificial Intelligence/Machine Learning Assays/Assay Development Augmented Reality Applications Automated Chemical Synthesis Barcode Readers & Labeling Cell Cultures/Apparatus/Supplies Chemical Synthesis Reagents Chromatography Clinical Automation/CLIA Clinical/Pre-clinical Diagnostics Compound Libraries Compound Screening Libraries Computer Hardware/Software Consulting Services Contract Services Data Analysis DNA-Encoded Libraries Detection Systems稀释剂/分配器电泳设备/用品外壳和引擎盖实验室设计与工程过滤设备和供应流式细胞仪:电动机,泵,泵,阀荧光测定荧光设备和供应通用实验室设备和供应基因工程
The NadA component is a fragment of the full-length protein derived from N. meningitidis strain 2996 (peptide 8 variant 2/3) 1 . The NHBA component is a recombinant fusion protein comprised of NHBA (peptide 2) 1 and accessory protein 953 derived from N. meningitidis strains NZ98/254 and 2996, respectively. The fHbp component is a recombinant fusion protein comprised of fHbp (variant 1.1) 1 and the accessory protein 936 derived from N. meningitidis strains MC58 and 2996, respectively. These 3 recombinant proteins are individually produced in Escherichia coli and purified through a series of column chromatography steps. The OMV antigenic component is produced by fermentation of N. meningitidis strain NZ98/254 (expressing outer membrane protein Porin A [PorA] serosubtype P1.4) 2 , followed by inactivation of the bacteria by deoxycholate, which also mediates vesicle formation. The antigens are adsorbed onto aluminum hydroxide.
1L First-line 2L Second-line ADA Anti-drug antibody ADME Absorption, distribution, metabolism, elimination ADT Androgen deprivation therapy AE Adverse event ALT Alanine aminotransferase AST Aspartate aminotransferase API Active pharmaceutical ingredient ATC Anatomical Therapeutic Chemical Classification System AUC Area under the plasma concentration-time curve AUC 24小时给药间隔BMI体重指数BRCA BRCA BRCA BRCA BRCA BRCA BSC最佳护理BSOC BSOC BSOC最佳护理CI置信区间C最大观察到血浆/血清的血清cRPC cRPC cRPC cRPC cRPC耐药性 - 耐药前列腺p450 dcr p450 dcr ddi ddi ddi ddi ddi ddi ddi ddi ddi ddi ddii Electrocardiogram ECOG Eastern Cooperative Oncology Group EMA European Medicines Agency ERA Environmental risk assessment ESI-MS Electrospray ionisation ESMO European Society for Medical Oncology FDA Food and Drug Administration (USA) GC Gas chromatography GLP Good Laboratory Practice HPLC High-performance liquid chromatography IC/EC 50 Half-maximal inhibitory/effective concentration ICH International Council for Harmonisation ICP-MS Inductively Coupled Plasma Mass Spectrometry Ig Immunoglobulin INN International non-proprietary name ITT Intention-to-treat LoQ List of Questions MAH Marketing Authorisation Holder Max Maximum MCBS Magnitude of Clinical Benefit Scale mCRPC Metastatic castration-resistant prostate cancer mHNPC Metastatic hormone-naïve prostate cancer Min Minimum MRHD Maximum recommended human dose MS Mass spectrometry MTD Maximum tolerated dose不适用NAAD新型雄激素轴药物NCCN国家综合癌症网络
OR-10-01审查软件工具的综述,这些软件工具简化了全面的二维气体色谱法(GCXGC)数据综述,以表征和区分复杂食品和饮料样品OR-10-01审查软件工具的综述,这些软件工具简化了全面的二维气体色谱法(GCXGC)数据综述,以表征和区分复杂食品和饮料样品
污染物检测需要非常灵敏且具有选择性的仪器和方法,例如色谱法和质谱法。色谱法可以分离分子以识别特定分子(选择性),而质谱仪则可以检测微量物质(低至十亿分之一)。Cotecna 实验室配备了创新技术,可以检测食品中的各种污染物,例如:> 农药残留> 霉菌毒素> 重金属> 工艺污染物(3-MCPD、丙烯酰胺、呋喃等)> 持久性有机污染物(持久性有机污染物、异丙醇、二恶英、多氯联苯等)> 药物> MOSH/MOAH(矿物油的饱和烃或芳香烃)> PFAS/PFOS(全氟和多氟烷基物质,它们是环境中的持久性污染物,可以迁移到食品和饲料中)。
脂肪TES-AC-536使用Weibull-Stoldt提取(酸水解),然后通过溶剂萃取牛奶和牛奶产品进行溶剂提取和粗脂脂肪脂肪1)使用Rose-Gottlieb提取2)TES-AC-202 TES-GOTTLIEB提取2)TES-AC-268 TES-AC-268通过Gerber方法,基于BS ISO 488:2008:2008,2446:2008,2446:2008,2446:2008,2446:2008,2446:2008,2446:2008,2446:2008,2446: 696-2:1989 (superseded and withdrawn) for milk products General Butter fat content (milk fat) TES-AC-537 analysis of butyric acid methyl ester after trans-esterification of fat using gas chromatography with flame ionisation detector (GC/FID) General Fatty acid profile TES-AC-090 using GC/FID General Fibre - Crude fibre TES-AC-226 based on “The Feed (Sampling and Analysis and根据AOAC国际杂志,饮食纤维TES-AC-203在102°C一整夜烤箱干燥后,2010年的特定不良物质)(英格兰)法规“ 2010年”。 mg/kg)
2.我们生产一系列电子仪器,用于环境分析和排放监测、工业过程控制、石化制造、半导体制造、药物发现以及能源勘探和生产。环境和实验室仪器包括 Teledyne Advanced Pollution Instrumentation 和 Teledyne Monitor Labs 空气质量监测仪器和系统、Teledyne Isco 废水采样器和快速色谱设备、Teledyne Tekmar 气相色谱样品浓缩器和总有机碳分析仪以及 Teledyne Leeman Labs 元素光谱仪和汞分析仪。工业仪器包括用于海上石化勘探的地球物理传感器、Teledyne Hastings 真空计和质量流量控制器以及 Teledyne Analytical Instruments 氧气传感器。
带有质谱(GC/MS)的气相色谱法是识别多种气体和挥发性有机成分的金标准技术。色谱分离后,质谱仪将分子成分分解为片段离子的特征模式。使用商业光谱数据库和解释确定了这些模式,而不严格依赖历史色谱数据的内部库。质谱的另一个好处是,方法修改不会影响识别组件的能力,因此可以优化一般方法以更好地靶向一个或多个组件。该技术的局限性包括GC/MS无法检测氢或氟化物气体的能力,以及对定量分析的可靠性的可能担忧。
目的:我们的实验室采用新方法分析毒理学样本和药物材料中的药物,通过气相色谱质谱法 (GC-MS) 和液相色谱四极杆飞行时间质谱法 (LC-QTOF-MS) 进行全面的非靶向数据采集。分析范围涵盖 1,200 多种药物,包括绝大多数 NPS 及其代谢物。这种方法可以实时识别新的苯二氮卓类药物并进一步分析重要趋势的数据。与我们的结果相关的样本和样品类型来自娱乐性药物材料、药物设备、法医死亡调查、临床中毒和/或酒驾调查等情况。本报告总结了本季度 CFSRE 识别的 NPS 总数,包括样本挖掘、数据挖掘、常规测试和深奥测试的结果。