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isatuximab，pomalidomide和地塞米松作为打捞
恩里卡·安东尼亚·马蒂诺（Enrica Antonia Martino），丹尼尔·德鲁达斯（Daniele Derudas），埃琳娜·罗西（Elena Rossi），索菲亚·特里兹（Sofia Terlizzi），乔瓦尼（Giovanni） O，Roberta Della Pepa，Giuseppe Bertuglia，Emiliano Barbieri，Conchitale，Conconce。 Claudio de Magistris，Lorenzo de Paoli，Velia Bongarzoni，Anna Maria Cafro，Anna Mele，Pietro Benvenuti，Claudio Cerchione，Cirino Botta，Elisabetta Antoniooli Bianco，Massimiliano Aragio Fabbo，Gloria Margio Casaluci， Angela Rago, Raffaele Fontana, Francesca Farina, Ernesto Vigna, Antonella Bruzzese, Katia Mancuso, Davide Nappi, Sonia Morè, Elena Rivati, Catello Califano, Angela Amendola, Daniela Roccotelli, Alessandra Lombardo, Annalisa Citro, Giuseppina Bartcello, Renato Zambello, Alessandro Maggi, Santo Neri, Michele Monachesi, Alessandro Gozzetti, Vittorio Montefusco, Vittorio Montefusco. Marino Bruori，Emilia Cotzia，Giuseppe Pietrantuono，Angela Maria Quinto，Valeria Amico，Nicola di Renzo，Marta Coscia，Monica Galli，Valerio de Stefano，Maria Teresa Petrucci，Antonino neri neri ando， ：2024年9月15日。接受：2024年11月11日。 iSatuximab，pomalidomide和地塞米松作为患者多发性骨髓瘤的挽救疗法：意大利，多中心，回顾性临床经验，在对照临床试验之外，有270例病例。 血液学。 2024年11月28日。doi：10.3324/haematol.2024.286658 [Epub在印刷前]出版商的免责声明。iSatuximab，pomalidomide和地塞米松作为患者多发性骨髓瘤的挽救疗法：意大利，多中心，回顾性临床经验，在对照临床试验之外，有270例病例。血液学。2024年11月28日。doi：10.3324/haematol.2024.286658 [Epub在印刷前]出版商的免责声明。引用：Enrica Antonia Martino，Daniele Derudas，Elena Rossi，Sofia Terlizzi，Giovanni Reddicto，Paola Stefanoni，Jacopo Micozzi，Silvia Mangiacavali Aro，Roberta Della Pepa，Giuseppe Bertuglia，Emiliano Barbieri，Concetta Concetta Concetta Corticello，Claudio de Magistris，Lorenzo de Paoli，Velia Bongarzoni，Anna Maria Cafro，Anna Mele，Anna Mele，Pietro Benvenuti，Claudio Cerchione，Cirino Botta，Elisabetta botta，Elisabetta Rosario Bianco，Massimiliano Arangio Fabbo，Gloria Margiotta，Gloria Margiotta。 Casaluci, Angela Rago, Raffaele Fontana, Francesca Farina, Ernesto Vigna, Antonella Bruzzese, Katia Mancuso, Davide Nappi, Sonia Morè, Elena Rivati, Catello Califano, Angela Amendola, Daniela Roccotelli, Alessandra Lombardo, Annalisa Citro, Giuseppina Bird, Renato Zambello, Alessandro Maggi, Santo Neri, Michele Monachetti, Vittorio, Montefusco，Marino Bruori，Emilia Cotzia，Giuseppe Pietrantuono，Angela Maria Quinto，Valeria Amico，Nicola di Renzo，Marta Coscia，Monica Coscia，Monica Galli，Valerio de Stefano，Maria teresa petrucci，anterino neriboto，forto dii dii dii dii dii Massimo Gentile。e-发布在印刷前对于快速传播科学至关重要。因此，所有适用于该期刊的法律免责声明也与该生产过程有关。在印刷之前发行电子版本后，手稿将进行技术和英语编辑，排版，证明校正和呈现以供作者的最终批准；然后，手稿的最终版本将出现在日记的常规期刊中。
多电源EM免疫的实验表征
Johannes W. M. Osterrieth，James Ramper，David Madden，Nakul Rampal，Luke Skoric，Bethany Connolly，Mark。 Santos，Xian-He Sun，Hana Bunzen，Sateh C. Moreton，Jessica C. Moreton。 M. D'Alessandro，Patrick W. Dohenn，MirceaDincă，Chenyue Sun，Christian Doonan，Michael Thomas Huxley，Jack D. Evans，Paolo Falcaro。 Shuhei Furukawa, Eli Sanchez, Jorge Gascon, Selvedin Telalović, Sujit K. Ghosh, Soumya Mukherjee, Matthew R. Hill, Muhammed Munir Sadiq, Patricia Horcajada, Pablo Salcedo-Abraira, Katsumi Kaneko, Radovan Kukobat, Jeff Kenvin, Seda Keskin, Susumu北川。Johannes W. M. Osterrieth，James Ramper，David Madden，Nakul Rampal，Luke Skoric，Bethany Connolly，Mark。 Santos，Xian-He Sun，Hana Bunzen，Sateh C. Moreton，Jessica C. Moreton。 M. D'Alessandro，Patrick W. Dohenn，MirceaDincă，Chenyue Sun，Christian Doonan，Michael Thomas Huxley，Jack D. Evans，Paolo Falcaro。 Shuhei Furukawa, Eli Sanchez, Jorge Gascon, Selvedin Telalović, Sujit K. Ghosh, Soumya Mukherjee, Matthew R. Hill, Muhammed Munir Sadiq, Patricia Horcajada, Pablo Salcedo-Abraira, Katsumi Kaneko, Radovan Kukobat, Jeff Kenvin, Seda Keskin, Susumu北川。A. Dewitt，免费V. Lotsch。拉玛·奥克塔维安（Rama Octavian），俄罗斯莫里斯（Morris），保罗·圣惠特利（Paul St. Wheatley），纳瓦尔（Navarre Cyderius，Randall Q. Snurr，Rebecca B. Concalves，Shane Telfer，Seok J. Lee，Valska P. Ting，Van Speybroeck，Sven M. Rogge，Krista，Christ。 St. Luke W. Bingel，Stefan Wuttke，Andreo Jacopo，Omar Yaghi。
TP53 基因破坏是靶向治疗时代的一个风险因素：一项针对 525 例慢性淋巴细胞白血病病例的多中心回顾性研究
Mauro Francesca（OrcID ID：0000-0003-2425-9474）REDA GIANLUIGI（ORCID ID：0000-0003-4687-7089）LAURENTI LUCA（ORCID ID ID：0000-0002-8327-1396） ：0000-0001-7304-1629）Visentin Andrea（OrcID ID：0000-0003-0271-7200）Moia Riccardo（OrcID ID ID：0000-0001-739 SARA 2-4620-0038） -0001-9047-5912）Cutrona Giovanna（OrcID ID：0000-0003-3013-ORCID：0000-000-0003-4026-285X）Gentile Massimo（OrcID ID：0000-0002-5256-0726） YMPHOCYTIC患者接受了新的CLL药物治疗：TP53 S Fortunato Morabito 1,2，Giovanni del Poeta 3，Francesca Romana Mauro 4，Gianluigi Reda 5，Paolo Sportoletti 6，Luca Laurenti 7，Marta Coscia 8，Marta Coscia 8，Yair Herishanu 9，sabiia sariio sariio sariio sariio sariio sariio sabria sariio sariio sabria U ndrea Visentin 13，Adalgisa Condoluci 14，Riccardo Moia 15，Daniela Pietrasanta 16，Giacomo Loseto 17，Ugo Consoli 18，Ilaria Scortechini 19 Ernesto Vigna 21，Giovanni Trivepi 22，Graziella d'Arrigo 22，Sara Galimberti 23，Angela Rago 24，Ilaria Angeletti 25，Annalisa Biagi 3，Ilaria del Giudicetti，Riccar 24，Riccar 20，Riccar 20 Rossi 14，Francesco di Raimondo 12，Antonio Cuneo 30，Gianluca Gaidano 15，Aaron Polliack 31，Livio Trent 13，Robin Folio 34，Valter Gattei 20*，Massimo Gentile 21*。 *VG 和 MG 作为资深作者做出了同等贡献
作者：Patrick A. Champlin - DSpace@MIT
对各种交叉技术（包括核相关和非核相关技术）的经济潜力和准备情况进行了评估，发现 2030 年之前开始建设的新核电厂的 LCOE 净减少量可达 28-38%，之后最多可减少 65%。短期效益主要来自几种降低资本成本的技术，例如抗震隔离（7-10%）、钢板复合材料和超高性能混凝土（6-8%）、机械部件的模块化结构（4-5%）和高强度钢筋（~2%），而传热涂层（~5%）是唯一具有可比影响的非资本技术。长期效益也主要归功于资本技术，其中大型金属部件的增材制造（3-9%）和海上选址（3-9%）占了大部分效益增长。现有核电站同样有望获利，改造后可在短期内节省相当于 6-8% 的 LCOE 成本，这主要归功于上述涂层。评估的其他技术包括事故容错燃料、先进仪器和控制、先进动力循环、嵌入、能量存储和机器人技术。自三哩岛核事故以来，美国核电站的夜间成本和施工时间增加了两倍，因此此类技术具有巨大的潜力来帮助陷入困境的行业。值得注意的是，这些估计不包括从积累的施工经验中学习到的知识，这可以额外将 LCOE 降低 20-40%，并且是小型模块化反应堆的驱动因素，或从布雷顿循环的次要目标等来源增加收入，这被发现是选择此类替代方案的最可能动机，以及能量存储，其中热存储被确定为最适合核电站。此外，一旦超过相对较低的阈值，传热涂层的耐久性就被认为比热性能对其可行性更重要。尽管上述值定义了可行的节省范围，但在实施过程中必须小心谨慎才能实现这些节省。例如，如果过快实施过多模块化结构，则可能会出现问题，因为它通常不如传统结构灵活。在最近的美国 AP1000 建设中观察到了这个问题。论文指导老师：Jacopo Buongiorno 东京电力公司教授、麻省理工学院核科学与工程系副主任、先进核能系统中心 (CANES) 主任 论文阅读者：David Petti 首席核科学家、研发主任和 INL 实验室研究员
金融技术采用：墨西哥无现金支付的网络外部性
* 西北大学凯洛格管理学院金融系（电子邮件：sean.higgins@kellogg.northwestern.edu）。埃丝特·迪弗洛 (Esther Duflo) 是本文的共同编辑。 I am Grateful to Paul Gertler, Ulrike Malmendier, Fred Finan, and David Sraer for Guidance and Support, As Bibek Adhikari, David Atkin, Pierre Bachas, Giorgia Barboni, Matteo Benetton, Josh Blumenstock, zerek brat-gold, Ben Charoenwong ( Discussant ) , Anthony Defusco, Carola Frydman, Virginia Gianinazzi ( Discussant ) Sylvan Herskowitz, Bob Hunt , Seema Jayachandran, John Loeser, Nora Lustig, Ted Miguel, luu Nguyen, Waldo Ojeda, Jacopo Prabby ( Dis- Cussant , Michael nt ) , Betty Sadoulet, Emmanuel Saez, Discusant , Gabriel Zucman, and Seminar Partipants, Atlanta Fed, Bank of Israel, Bocconi, Cambridge, Cepr, Dartmouth, GSU-RFS, idas, , Inter-American Development Bank, Illinois, London School of Economics, neudc, northwestern, Nyu, Penn, Princeton, Princeton, Sfs Cavalcade, Stanford, UC Diego , UNC, University of San Francisco, UT Austin, Wfa, World Bank, Wvu, and Yale y-rise for comments that helply improve the paper.我感谢 Saul Knight、Arthur Charleston、Nils Lieber、Jora Li、Xinghuan Luo、Eric Molina、Anah Kings、Carlos Restituyo 和 Angelyna Ye 提供的研究协助。我感谢墨西哥以下机构的官员提供数据访问并回答问题。墨西哥银行：Marco Acosta、Biliana Alexandrova、Sara Castellanos、Miguel Angel Diaz、Lorenza Martinez、Othon Moreno、Samuel Navarro、Axel Vargas 和 Rafael Villar。 Bansefi: Virgil Andrade, Benjamin Chacon, Miguel Angel Lara, Oscar Moreno, Ramon Sanchez, and Ana Lilia Urquieta. CNBV: Rodrigo Aguirre, Alvaro Melendez Martinez, Diana Radilla, and Gustavo Salaiz. INEGI：Gerardo Leyva 和 Natalia Volkow。繁荣：Martha Cuevas、Armando Geronimo、Rogelio Grados、Raul Perez、Rodolfo Sanchez、Jose Solis 和 Carla Vazquez。本研究项目中表达的结论由我作为作者独自负责，并且不属于国家统计和地理信息系统 (INEGI) 的官方统计数据。非常感谢墨西哥银行夏季研究项目的资助。 IRB 批准：IPA 00006083、西北大学 STU00217227 和加州大学伯克利分校 2018-02-10796。 † 请访问 https://doi.org/10.1257/aer.20201952 获取更多材料和作者披露声明。
通过 BET 方程计算的表面积的可重复性如何？
Johannes WM Osterrieth, James Rampersad, David Madden, Nakul Rampal, Luka Skoric, Bethany Connolly, Mark D. Allendorf, Vitalie Stavila, Jonathan L. Snider, Rob Ameloot, João Marreiros, Conchi Ania, Diana Azevedo, Enrique Vilarrasa-Garcia, Xinca F, Buan, Buan, Hanze, Hanze, Neil. R. Champness, Sarah L. Griffin, Banglin Chen, Rui-Biao Lin, Benoit Coasne, Seth Cohen, Jessica C. Moreton, Yamil J. Colón, Linjiang Chen, Rob Clowes, François-Xavier Coudert, Yong Cui, Bang Hou, Deanna M. D'Alessandro, Payne Dohen, Doen, Doe, Sun, Christian. Michael Thomas Huxley, Jack D. Evans, Paolo Falcaro, Raffaele Ricco, Omar Farha, Karam B. Idrees, Timur Islamoglu, Pingyun Feng, Huajun Yang, Ross S. Forgan, Dominic Bara, Shuhei Furukawa, Eli Sanchez, Jorge Gascon, Selvedin Telalović, Sukho Khamed, Khammed Murji, Murji Murji, Matthew R. Saum. diq, Patricia Horcajada, Pablo Salcedo-Abraira, Katsumi Kaneko, Radovan Kukobat, Jeff Kenvin, Seda Keskin, Susumu Kitagawa, Ken-ichi Otake, Ryan P. Lively, Stephen JA DeWitt, Phillip Llewellyn, Bettina V. Lotsch, Sebastian T. Ender, Alexander M. Pati M. Pati M. al, Javier García-Martínez, Noemi Linares, Daniel Maspoch, Jose A. Suárez del Pino, Peyman Moghadam, Rama Oktavian, Russel E. Morris, Paul S. Wheatley, Jorge Navarro, Camille Petit, David Danaci, Matthew J. Rosseinsky, Alexandros P., Kat Schunder, Martin Xu, Sergeant, Sergian, Sergeant. s Mouchaham, David S. Sholl, Raghuram Thyagarajan, Daniel Siderius, Randall Q. Snurr, Rebecca B. Goncalves, Shane Telfer, Seok J. Lee, Valeska P. Ting, Jemma L. Rowlandson, Takashi Uemura, Tomoya Iiyuka, Monique A. van der Revere, David Revere, Speed, M.J. and Lamaire, Krista S. Walton, Lukas W. Bingel, Stefan Wuttke, Jacopo Andreo, Omar Yaghi, Bing Zhang, Cafer T. Yavuz, Thien S. Nguyen, Felix Zamora, Carmen Montoro, Hongcai Zhou, Angelo Kirchon, and David Fairen-Jimenez*
通过 BET 方程计算的表面积的可重复性如何？
Johannes WM Osterrieth, James Rampersad, David Madden, Nakul Rampal, Luka Skoric, Bethany Connolly, Mark D. Allendorf, Vitalie Stavila, Jonathan L. Snider, Rob Ameloot, João Marreiros, Conchi Ania, Diana Azevedo, Enrique Vilarrasa-Garcia, Xinca F, Buan, Buan, Hanze, Hanze, Neil. R. Champness, Sarah L. Griffin, Banglin Chen, Rui-Biao Lin, Benoit Coasne, Seth Cohen, Jessica C. Moreton, Yamil J. Colón, Linjiang Chen, Rob Clowes, François-Xavier Coudert, Yong Cui, Bang Hou, Deanna M. D'Alessandro, Payne Dohen, Doen, Doe, Sun, Christian. Michael Thomas Huxley, Jack D. Evans, Paolo Falcaro, Raffaele Ricco, Omar Farha, Karam B. Idrees, Timur Islamoglu, Pingyun Feng, Huajun Yang, Ross S. Forgan, Dominic Bara, Shuhei Furukawa, Eli Sanchez, Jorge Gascon, Selvedin Telalović, Sukho Khamed, Khammed Murji, Murji Murji, Matthew R. Saum. diq, Patricia Horcajada, Pablo Salcedo-Abraira, Katsumi Kaneko, Radovan Kukobat, Jeff Kenvin, Seda Keskin, Susumu Kitagawa, Ken-ichi Otake, Ryan P. Lively, Stephen JA DeWitt, Phillip Llewellyn, Bettina V. Lotsch, Sebastian T. Ender, Alexander M. Pati M. Pati M. al, Javier García-Martínez, Noemi Linares, Daniel Maspoch, Jose A. Suárez del Pino, Peyman Moghadam, Rama Oktavian, Russel E. Morris, Paul S. Wheatley, Jorge Navarro, Camille Petit, David Danaci, Matthew J. Rosseinsky, Alexandros P., Kat Schunder, Martin Xu, Sergeant, Sergian, Sergeant. s Mouchaham, David S. Sholl, Raghuram Thyagarajan, Daniel Siderius, Randall Q. Snurr, Rebecca B. Goncalves, Shane Telfer, Seok J. Lee, Valeska P. Ting, Jemma L. Rowlandson, Takashi Uemura, Tomoya Iiyuka, Monique A. van der Revere, David Revere, Speed, M.J. and Lamaire, Krista S. Walton, Lukas W. Bingel, Stefan Wuttke, Jacopo Andreo, Omar Yaghi, Bing Zhang, Cafer T. Yavuz, Thien S. Nguyen, Felix Zamora, Carmen Montoro, Hongcai Zhou, Angelo Kirchon, and David Fairen-Jimenez*
通过 BET 方程计算的表面积的可重复性如何？
Johannes WM Osterrieth, James Rampersad, David Madden, Nakul Rampal, Luka Skoric, Bethany Connolly, Mark D. Allendorf, Vitalie Stavila, Jonathan L. Snider, Rob Ameloot, João Marreiros, Conchi Ania, Diana Azevedo, Enrique Vilarrasa-Garcia, Xinca F, Buan, Buan, Hanze, Hanze, Neil. R. Champness, Sarah L. Griffin, Banglin Chen, Rui-Biao Lin, Benoit Coasne, Seth Cohen, Jessica C. Moreton, Yamil J. Colón, Linjiang Chen, Rob Clowes, François-Xavier Coudert, Yong Cui, Bang Hou, Deanna M. D'Alessandro, Payne Dohen, Doen, Doe, Sun, Christian. Michael Thomas Huxley, Jack D. Evans, Paolo Falcaro, Raffaele Ricco, Omar Farha, Karam B. Idrees, Timur Islamoglu, Pingyun Feng, Huajun Yang, Ross S. Forgan, Dominic Bara, Shuhei Furukawa, Eli Sanchez, Jorge Gascon, Selvedin Telalović, Sukho Khamed, Khammed Murji, Murji Murji, Matthew R. Saum. diq, Patricia Horcajada, Pablo Salcedo-Abraira, Katsumi Kaneko, Radovan Kukobat, Jeff Kenvin, Seda Keskin, Susumu Kitagawa, Ken-ichi Otake, Ryan P. Lively, Stephen JA DeWitt, Phillip Llewellyn, Bettina V. Lotsch, Sebastian T. Ender, Alexander M. Pati M. Pati M. al, Javier García-Martínez, Noemi Linares, Daniel Maspoch, Jose A. Suárez del Pino, Peyman Moghadam, Rama Oktavian, Russel E. Morris, Paul S. Wheatley, Jorge Navarro, Camille Petit, David Danaci, Matthew J. Rosseinsky, Alexandros P., Kat Schunder, Martin Xu, Sergeant, Sergian, Sergeant. s Mouchaham, David S. Sholl, Raghuram Thyagarajan, Daniel Siderius, Randall Q. Snurr, Rebecca B. Goncalves, Shane Telfer, Seok J. Lee, Valeska P. Ting, Jemma L. Rowlandson, Takashi Uemura, Tomoya Iiyuka, Monique A. van der Revere, David Revere, Speed, M.J. and Lamaire, Krista S. Walton, Lukas W. Bingel, Stefan Wuttke, Jacopo Andreo, Omar Yaghi, Bing Zhang, Cafer T. Yavuz, Thien S. Nguyen, Felix Zamora, Carmen Montoro, Hongcai Zhou, Angelo Kirchon, and David Fairen-Jimenez*
通过 BET 方程计算的表面积的可重复性如何？
Johannes WM Osterrieth, James Rampersad, David Madden, Nakul Rampal, Luka Skoric, Bethany Connolly, Mark D. Allendorf, Vitalie Stavila, Jonathan L. Snider, Rob Ameloot, João Marreiros, Conchi Ania, Diana Azevedo, Enrique Vilarrasa-Garcia, Xinca F, Buan, Buan, Hanze, Hanze, Neil. R. Champness, Sarah L. Griffin, Banglin Chen, Rui-Biao Lin, Benoit Coasne, Seth Cohen, Jessica C. Moreton, Yamil J. Colón, Linjiang Chen, Rob Clowes, François-Xavier Coudert, Yong Cui, Bang Hou, Deanna M. D'Alessandro, Payne Dohen, Doen, Doe, Sun, Christian. Michael Thomas Huxley, Jack D. Evans, Paolo Falcaro, Raffaele Ricco, Omar Farha, Karam B. Idrees, Timur Islamoglu, Pingyun Feng, Huajun Yang, Ross S. Forgan, Dominic Bara, Shuhei Furukawa, Eli Sanchez, Jorge Gascon, Selvedin Telalović, Sukho Khamed, Khammed Murji, Murji Murji, Matthew R. Saum. diq, Patricia Horcajada, Pablo Salcedo-Abraira, Katsumi Kaneko, Radovan Kukobat, Jeff Kenvin, Seda Keskin, Susumu Kitagawa, Ken-ichi Otake, Ryan P. Lively, Stephen JA DeWitt, Phillip Llewellyn, Bettina V. Lotsch, Sebastian T. Ender, Alexander M. Pati M. Pati M. al, Javier García-Martínez, Noemi Linares, Daniel Maspoch, Jose A. Suárez del Pino, Peyman Moghadam, Rama Oktavian, Russel E. Morris, Paul S. Wheatley, Jorge Navarro, Camille Petit, David Danaci, Matthew J. Rosseinsky, Alexandros P., Kat Schunder, Martin Xu, Sergeant, Sergian, Sergeant. s Mouchaham, David S. Sholl, Raghuram Thyagarajan, Daniel Siderius, Randall Q. Snurr, Rebecca B. Goncalves, Shane Telfer, Seok J. Lee, Valeska P. Ting, Jemma L. Rowlandson, Takashi Uemura, Tomoya Iiyuka, Monique A. van der Revere, David Revere, Speed, M.J. and Lamaire, Krista S. Walton, Lukas W. Bingel, Stefan Wuttke, Jacopo Andreo, Omar Yaghi, Bing Zhang, Cafer T. Yavuz, Thien S. Nguyen, Felix Zamora, Carmen Montoro, Hongcai Zhou, Angelo Kirchon, and David Fairen-Jimenez*
实验性癫痫的讨论 3
罗马第一大学 – Piazzale Aldo Moro 5 10:00 – 10:15 欢迎 – 系主任 Eleonora Palma 介绍 – Cinzia Costa 和 Eleonora Palma 10:15 – 12:00 主席：Maurizio Taglialatela – Gaetano Terrone 10:15 – 10:30 以多巴胺能和内源性大麻素信号传导为目标进行救援Lafora 病小鼠模型中的突触功能障碍 Sciaccaluga Miriam 10:30 – 10:45 癫痫持续状态会触发致痫性皮质畸形的 MAM/毛果芸香碱大鼠模型中的中枢神经系统自身免疫反应 Ciotti Arianna 10:45 – 11.00 了解伴有癫痫发作的自身免疫性脑炎：揭示外周炎症作用的新实验方法 Prevosti萨拉 11:00 – 11:15 基于 GABAA 受体过度表达的局灶性癫痫基因治疗方法 Bettegazzi Barbara 11:15 – 11:30 追踪从肠道到大脑的代谢物：探索代谢组学和脂质组学方法研究癫痫的肠脑轴 Volpedo Greta 11:30 – 12:00 讨论 12:00 – 12:45 特邀嘉宾讲座 Albert Becker（波恩大学）– 由 Annamaria Vezzani 介绍 12:45 – 15:00 便餐 – 海报展示会（Filippo Sean Giorgi – Jacopo Di Francesco） 15:00 – 16:45 主席：Marco de Curtis – Michele Simonato 15:00 – 15:15 慢性去甲肾上腺素能失神经支配对老龄小鼠模型中癫痫发作阈值的影响：晚发型癫痫与癫痫发作之间可能存在的联系癫痫和阿尔茨海默病 Galgani Alessandro 15:15 – 15:30 AATrkB 激活作为药物耐药性颞叶癫痫的新靶点：从动物模型到人类癫痫大脑 Guarino Annunziata 15:30 – 15:45 大麻二酚在因 ARX 三联体重复扩增导致的发育性和癫痫性脑病小鼠模型中发挥抗癫痫作用并增加存活率 Verrillo Lucia 15:45 – 16:00 用于测试 GLUT -1 缺乏综合征新治疗策略的雨内皮模型 Baldassari Simona 16:00 – 16:15 SCN2A p.Asp195Gly 突变的特征：药物耐药性癫痫性脑病患者的功能丧失变体 Lo Presti Francesca 16:15 – 16:45 讨论16:45 – 17:00 与 YES（ILAE 青年癫痫科）Giulia Battaglia – Ganna Balagura 会面 17:00 – 18:00 结论 – Giuliano Avanzini、Oriano Mecarelli、Emilio Russo 奶酪和葡萄酒 口头陈述：英语，每次最长 15 分钟，包括结论的清晰摘要 海报：英语（最大 70x100 厘米）；请选择清晰的示意图结论和图表