在这些患者中,中位年龄为55岁(范围为29-73)。Most of the patients (66.7%) had stage III or IV disease, 41% had an ECOG performance status score of 2 or 3, 64.1% had extranodal organ involvement, 51.3% had received at least three lines of previous therapies, 46.2% had received more than 10 times of prior treatment regimen, 51.3% had refractory disease, 7.7% experienced autologous stem cell transplantation (ASCT) and 46.2%的笨重疾病被定义为具有超过7厘米直径的任何肿块的存在。