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人工智能在杂草管理中的应用，实现可持续发展……
Aarzoo* 1、Anjali Rana 2、Ravina Yadav 3 和 Sagar Saroha 4 研究学者 1、3&4、农学系 1&2、土壤科学系 3、花卉栽培系 4、CCS 哈里亚纳农业大学，Hisar-1504，哈里亚纳邦
PR Atlante TEDXPADOVA_ DEF ENG
Atlante 首席执行官 Stefano Terranova 表示：“Atlante 热情地自愿支持 TEDxPadova 项目，因为它分享了重要的价值观，例如创新、对人的热情和技术使命。正如 TED 的座右铭“值得传播的想法”所说，我们 Atlante 也相信，我们有想法可以分享，以改善地球的未来：我们已经将这些想法付诸行动，正如我们在帕多瓦建造的两个充电中心所看到的那样。在 Atlante，我们也非常喜欢 TEDxPadova 选择的“TEN”：它代表卓越。最后，就在十年前，一位才华横溢的年轻工程师 Giovanni Ravina 是第一届 TEDxPadova 的演讲者之一。今天，这位才华横溢的工程师是我们伊比利亚的首席执行官，也是 Atlante 本身的创造者之一。”
面试候选人最终名单*...
S. 编号 候选人姓名 面试模式 1. Aditya Raj 在线 2. Akash Bansod 在线 3. Ankit Verma 在线 4. Archana Shrichippa 在线 5. Ashif Ali 在线 6. Bhava Dharani 在线 7. Jicksy Jose 在线 8. Neha N. 在线 9. Nisha Nain 在线 10. Prashant Kumar 在线 11. Ravina Ramteke 在线 12. Ritupurna Dasgupta Online 13. Roshni Meghnani Online 14. Sakshi Agrawal Online 15. Samiksha Chavhan Online 16. Saroja Thota Online 17. Shree Yazhini V Online 18. Supratik Pal Choudhury Online 19. Supriya Kammar Online 20. Sunita Pradhan Online 21. Surbhi tripathi Online 22. Swarnendra banerjee Online 23. Tejas Nimkar 在线的
NeuroNEXT 和 NIH StrokeNet：NANDS 理事会临床网络评估工作组的报告
该工作组包括一名 NANDS 理事会成员、精通临床试验执行和网络协调的研究人员、精通网络所涉及研究领域的研究人员，以及来自行业和患者组织的代表。 Barbara Vickrey（联合主席），医学博士、公共卫生硕士，西奈山伊坎医学院 Richard Rudick（联合主席），医学博士，Optimal Brain Health Consultants Ed Trevathan，医学博士、公共卫生硕士，范德堡大学 Erika Augustine，医学博士、理学硕士，肯尼迪克里格研究所 Rebecca Gottesman，医学博士、哲学博士，NINDS 院内研究部 Bernard Ravina，医学博士，Praxis Precision Medicines Janet Hieshetter，肌张力障碍医学研究基金会 Traci Clemons，哲学博士，The Emmes Company，LLC Issam Awad，医学博士，芝加哥大学 Adrian Hernandez，医学博士，杜克大学医学院 E. Ray Dorsey，医学博士、工商管理硕士，罗彻斯特大学 评估流程和时间表
帕金森病和进展的遗传风险：
Hirotaka Iwaki, MD, Cornelis Blauwendraat, PhD, Hampton L. Leonard, MS, Ganqiang Liu, PhD, Jodi Maple-Grødem, PhD, Jean-Christophe Corvol, MD, PhD, Lasse Pihlstrøm, MD, PhD, Marlies van Nimwegen, PhD, Samantha J. Hutten, PhD, Khanh-Dung H. Nguyen, PhD, Jacqueline Rick, PhD, Shirley Eberly, MS, Faraz Faghri, MS, Peggy Auinger, MS, Kirsten M. Scott, MRCP, MPhil, Ruwani Wijeyekoon, MRCP, Vivianna M. Van Deerlin, MD, PhD, Dena G. Hernandez, PhD，Aaron G. Day-Williams，博士，Alexis Brice，医学博士，Guido Alves，MD，PhD，Alastair J. Noyce，MRCP，PhD，Ole-BjørnTysnes，MD，PhD，PhD，Jonathan R. Evans，Mrcp，Mrcp，Phd，Phd P. Breen，Mrcp，Mrcp，Phd，Phd，Phd，Ph. Fabrice Danjou，医学博士，博士，David K. Simon，医学博士，博士，伯纳德·拉维纳（Bernard Ravina）沃伦堡（Warrenburg）医学博士，Jacobus J.van Hilten，医学博士，博士，Clemens R. Scherzer，医学博士，Andrew B. Singleton，PhD和Mike A. Nalls，博士
Septins 破坏可控制肿瘤生长并增强赫赛汀的疗效
Septins disruption controls tumor growth and enhances efficacy of Herceptin 1 2 Rakesh K Singh* 1 , Kyu Kwang Kim 1 , Negar Khazan 1 , Rachael B. Rowswell-Turner 1 , Christian 3 Laggner 3 , Aaron Jones 1 , Priyanka Srivastava 1 , Virginia Hovanesian 4 , Liz Lamere 1 , Thomas 4 Conley 1 , Ravina Pandita 1 , Cameron Baker 5 , Jason R Myers 5 , Elizabeth Pritchett 5 , Awada Ahmad 1 , 5 Luis Ruffolo 2 , Katherine Jackson 2 , Scott A. Gerber 2 , John Ashton 5 , Michael T. Milano 6 , David 6 Linehan 2 , Richard G Moore 1 7 8 1 Wilmot Cancer Institute, Division of Gynecologic Oncology, Department of Obstetrics and 9 Gynecology, University of Rochester Medical Center, Rochester, NY, USA. 10 2 Department of Surgery, Microbiology and Immunology; Department of Radiation Oncology and 11 Center for Tumor Immunology Research, University of Rochester Medical Center, Rochester, NY, 12 USA. 13 3 Atomwise Inc, San Francisco, CA, USA. 14 4 Rhode Island Hospital, Providence, RI, USA. 15 5 Genomics Research Center, Wilmot Cancer Center, University of Rochester Medical Center, NY, 16 USA. 17 6 Department of Radiation Oncology, University of Rochester, NY, USA. 18 19 20 * Corresponding author: 21 Rakesh_Singh@URMC.Rochester.Edu 22 Telephone (office): 585-276-6281. Fax: 585-276-2576 23 24 Abstract 25 Septin expressions are altered in cancer cells and exhibit poor prognoses in malignancies. As the 26 first approach to develop a septin filament targeting agent, we optimized the structure of 27 Forchlorfenuron (FCF), a known plant cytokinin to generate UR214-9, which contrary to FCF, 28 causes septin-2/9 filamental structural catastrophe in cancer cells without altering cellular septin 29 protein levels. In-silico docking using septin-2/septin-2 dimer complex showed that UR214-9 30 displaced the guanine carbonyl oxygen from the GDP binding domain and showed increased 31 binding energy than FCF(-8.59vs-7.21). UR214-9 reduced cancer cell growth, downregulated 32 HER2/STAT-3 axis and controlled growth of HER2+ pancreatic, breast and ovarian cancer 33 xenografts in NSG mice and enhanced response of Herceptin against HER2+breast cancer 34 xenograft. Transcriptome analysis of UR214-9 exposed cells demonstrated significant 35 perturbation of <20 genes compared to afatinib which impacted >1200 genes in JIMT-1 breast 36 cancer cells indicating target specificity and non-transcriptional functions of UR214-9. In summary, 37 disrupting septins via UR214-9 is a new approach to control the growth of HER2+ malignancies. 38 39 Introduction 40 41 Septins are a family of GTP-binding cytoskeletal proteins that participate in cytokinesis, 42 cell migration, chromosomal dynamics and protein secretion. Septins hetero-oligomerize to 43 generate scaffolding filaments, bundles, and rings within cells 1-11 . Additionally, septins are a 44 critical cytoskeletal component that regulate the function of tubulin and actin. Altered septin 45