Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide
Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticideAbstractBACKGROUNDThe toxin peptide U1-AGTX-Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.RESULTSU1-AGTX-Ta1b has inse
Gene-editing nanoparticle system targets multiple organs simultaneously
通过UT西南医学中心研究人员开发的基因编辑递送系统,同时针对的是一种罕见遗传疾病的临床前模型的肝脏和肺,该模型被称为Alpha-1抗胰蛋白酶缺乏症(AATD),在一次治疗后几个月来显着改善症状,这是一项新研究后的几个月。这些发现在自然生物技术中发表,可能会导致针对影响多个器官的各种遗传疾病的新疗法。