探索蝎子毒液减轻鼠尾草癌直肠癌(CRC)中结直肠癌生物标志物(CRC)的治疗潜力是全球与癌症相关死亡率的第二大主要原因。常规疗法的局限性,即严重的副作用和耐药性的出现,强调了对新颖和更有效的治疗策略的迫切需求。在各种研究中,天然产物(包括源自蝎子毒液(SV)的生物活性化合物)表现出了有希望的抗癌特性。这项研究旨在研究Leiurus Quinquestriatus毒液(LQV)和双二乳毒素毒液(ABV)对大鼠模型中化学诱导的CRC的潜在化学预防和治疗作用。 Male rats were randomly assigned to four groups: Group 1 (Gp1) (contro
实验研究的最佳缩放统计设计,以模拟撒哈拉以南非洲可用的蛇形抗蛇子的优先级,用于治疗蛇咬的蛇咬伤:来自加纳亚纳布尔素毒素的观点,来自加纳布拉素的低位和中等收入国家(LMIC)(LMICS)与热带或亚热带的质量率,并在高度范围内(s)求发。 高的。医护人员与患者一起是抗蛇毒的最终用户。 This study aimed to assess healthcare workers' antivenom prioritization by providing quantitative evidence to guide policymakers to make better decisions to i
Physical exercise and a nutritious diet can fight dementia
See Scientists Are Finally Making Progress Against Alzheimer’s: New drugs show promise, and research finds value in vaccines, antivirals, exercise and probiotics by "Lifestyle changes can augment the benefits. A recently published randomized trial found that a “treatment” of regular physical and cog
"I Gotta Own It": Bill Maher Admits He Was Dead Wrong About Trump Tariffs, 'Does Not See A Country In Depression'Left wing comedian Bill Maher admitted on Monday that he was dead wrong about the effect of President Trump's tariffs - saying in an episode of his "Club Random"podcast that while many ec
Passport Services: The National Passport Information Center Has Taken Steps to Meet Customer Needs
GAO发现了国家集中式客户服务呼叫中心,国家护照信息中心(NPIC),通过回答有关护照,提供护照申请援助并安排紧急护照预约的情况下的情况,在诸如生死攸关的情况等情况下,协助客户。 NPIC通过与护照相关的问题为客户保留免费电话号码和电子邮件地址。 In addition, NPIC has a dedicated telephone line and email address to assist congressional staffers with similar requests on behalf of their constituents.Customers who were ran
哈耶克的混蛋:奎因·斯洛博迪安(Quinn Slobodian)的民粹主义者的新自由主义根源,企鹅兰登书屋(Penguin Random House)的前提是奎因·斯洛博迪安(Quinn Slobodian)的前提……继续阅读“书评:哈耶克的混蛋”邮政图书评论:Hayek的杂物在经济事务研究所首次出现。
Vitamin D Supplements May Slow Process Linked To Aging, New Study Says
维生素D补充剂可能会减慢与衰老有关的过程,杰克·菲利普斯(Jack Phillips)通过《时报》(Epoch Times)(强调我们的)进行了新的研究,周四发表的一项研究发现,较高的维生素D摄入量的人可能会减慢与衰老相关的过程。 Justin Sullivan/Getty ImagesIn a paper released by the American Journal of Clinical Nutrition on May 22, Mass General Brigham and the Medical College of Georgia researchers looked at r
No Evidence of Effects of Testosterone on Economic Preferences
From Tyler Cowen."There is conflicting evidence on whether testosterone affects economic preferences such as risk taking, fairness and altruism, with the evidence suggesting significant effects coming from correlational studies or small underpowered testosterone administration studies. To credibly t
Experiments Illustrated: How We Optimized Premium Listings on Our Nursing Job Board
此外,Georandomization如何帮助清理溢出,邮政实验说明:我们如何优化护理工作委员会的高级清单首先出现在数据科学方面。
Soft Computing. Volume 29, Issue 3, February 2025
1) Some new construction methods of similarity measure on picture fuzzy setsAuthor(s): Minxia Luo, Jianlei Gao, Wenling LiPages: 1273 - 12872) Arithmetic optimization algorithm with cosine transform-based two-dimensional composite chaotic mappingAuthor(s): Yi-Xuan Li, Jie-Sheng Wang, Xin-Ru MaPage
Ensemble Learning for Anomaly Detection
深入研究隔离森林模型以检测时间序列数据中的异常异常检测是任何组织必备的功能。通过检测异常和离群值,我们不仅可以识别看似可疑(或可能错误)的数据,还可以确定“正常”数据是什么样子。异常检测可以识别数据错误,从而成为强大数据治理系统的重要功能。对于分析而言,异常值在某些情况下(例如欺诈检测和预测性维护)可能是一个关注点。然而,随着数据的增长,异常检测会变得越来越困难。高维数据带有噪声,难以用于分析和洞察。大型数据集也可能存在错误和/或特殊情况。值得庆幸的是,集成学习带来了速度和效率,帮助我们处理高维数据并检测异常。什么是集成学习?集成学习是一种机器学习技术,它结合了多个单独模型的预测,以获得比任何
An Off-Beat Approach to Train-Test-Validation Split Your Dataset
确保小数据集分割的分布完整性使用 Microsoft Designer 生成我们都需要对总体进行抽样,以进行统计分析并获得见解。当我们这样做时,目的是确保样本的分布与总体的分布紧密匹配。为此,我们有各种方法:简单随机抽样(其中每个总体成员都有相同的被选中的机会)、分层抽样(包括将总体划分为子组并从每个子组中抽样)、聚类抽样(其中将总体划分为簇并随机选择整个簇)、系统抽样(包括选择总体的每第 n 个成员)等。每种方法都有其优势,并根据研究的特定需求和特点进行选择。在本文中,我们不会关注抽样方法本身,而是关注使用这些概念将用于机器学习方法的数据集拆分为训练-测试-验证集。这些方法适用于所有类型的表
2023 年计划委员会主席的客座帖子:Nicole Megow(APPROX)和 Adam Smith(RANDOM)第 27 届国际随机化和计算研讨会 (RANDOM 2023) 和第 26 届组合优化问题近似算法国际研讨会 (APPROX 2023) 将于 2023 年 9 月 11 日至 13 日在美国佐治亚州亚特兰大亲自举行。RANDOM 2023 专注于随机性在计算和组合问题中的应用,而 APPROX 2023 则专注于与开发计算难题的有效近似解有关的算法和复杂性理论问题。重要日期:提交:2023 年 5 月 4 日,18:00 EDT(UTC-4)通知:2023 年 6 月 26
In JAMA, Michelle Detry and Roger Lewis explain the “intention-to-treat” (ITT) principle: [I]n a trial in which patients are randomized to receive either treatment A or treatment B, a patient may be randomized to receive treatment A but erroneously receive treatment B, or never receive any treatment