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Bioassay • Uses a monocyte stable cell line • Measures the ability of antibody in activating the cells upon binding to target Y • Activation is measured by secretion of chemokine Z, positively correlates to the antibody concentration • Chemokine Z indicates monocyte activation to macrophage, but does not distinguish M2 vs M1 → the
生物测定生物测量生物学生物测量管理的监管考虑
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