Pregnancy should be planned, with the following steps taken prior to conception: • A1C 7% or less, but strive for ≤6.5% (ensure contraception until at personalized target) • Stop: - Non-insulin antihyperglycemic agents (except metformin and/or glyburide) - Statins - ACEi/ARB prior to pregnancy, but if overt nephropathy exists, continue until detection of pregnancy • Start: - Folic acid 1 mg per day x 3 months prior to conception - Insulin if target A1C is not achieved on metformin and/or glyburide (type 2) - Other antihypertensive agents safe for pregnancy (Labetalol, nifedepine XL) if hypertension control needed • Screen for complications: - Eye appointment, serum creatinine, urine ACR, blood pressure • Aim for healthy BMI • Ensure appropriate vaccinations have发生•参考糖尿病诊所