玛丽亚·布拉尼斯·莫雷拉（Maria Branyas Morera） - 1907年3月4日出生于旧金山，生于西班牙父母 - 在两次世界大战中幸存下来，西班牙流感，一场内战，以及最近的大流行。这超过了居住在西班牙加泰罗尼亚的妇女的平均预期寿命，她一生都在这里度过了30多年。这项成就使她成为了少数超级中心人之一，这是一个少数但越来越多的人来庆祝自己的110岁生日。 Now, a team of researchers writing in Cell Reports Medicine has published the findings of a comprehensive study examining samples collected from Branyas, offering clues that help explain her exceptional health and surprisingly long lifespan — including a predilection for yogurt.Describing the results in a press release, lead author Manel Esteller, Head of the Cancer Epigenetics group at the Josep Carreras Leukaemia Research Institute, pointed to a “fascinating duality” that displays “the simultaneous presence of signals of extreme aging and of healthy longevity.”Read More: More Time and Less Work Could Mean That Mental Health Increases as we AgeA “Fascinating Duality”Esteller and his team carried out a series of tests on blood, saliva, urine, and stool samples, the majority collected from Branyas when she was 116. This included sequencing the entirety of Branyas’ genome —这一过程揭示了与寿命和抗病性抗病性相关的各种结构变异，包括与优越的免疫功能和心脏健康相关的过程。