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源数据对发射车故障树模型的认知不确定性影响
抽象的发射车系统是使用遗产和新硬件设计和开发的。对遗产硬件的设计修改以适合新的功能系统要求可能会影响遗产可靠性数据的适用性。新设计系统的风险估计必须是从通用数据源（例如使用可靠性预测方法）（例如在MIL-HDBK-217F中涉及的方法）开发的。必须将故障估计值从通用环境转换为使用系统的特定操作环境。此外，应将数据源适用于当前系统的某些资格。在这种情况下表征数据适用性对于开发模型估算至关重要，这些模型估算支持对设计变化和贸易研究的自信决策。本文将展示一种基于原始数据的源和操作环境，建议对目标车辆的认知成分不确定性，以展示一种数据源适用性分类方法。使用启发式准则确定源适用性，而操作环境的翻译是通过将统计方法应用于MIL-HDK-217F表来完成的。
Investment Highlights
• First Australian Patient Dosed in Phase 1b Azer-cel Clinical Trial, Targeting Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL): Imugene Limited has announced that the first Australian patient has been dosed in the Phase 1b clinical trial of azer-cel (azercabtagene zapreleucel) at the Royal Prince Alfred Hospital (RPAH) in Sydney. Azer-cel is an allogeneic, off-the-shelf CAR T-cell therapy designed to shorten treatment timelines and expand accessibility for patients who have limited options, particularly those with challenging, aggressive forms of DLBCL. This announcement follows promising data from the Company's U.S. trial sites, where three patients achieved complete responses (CR) despite having failed multiple prior treatments. In Cohort B, which includes lymphodepletion chemotherapy and interleukin-2 (IL-2), responses have extended beyond 90 and 120 days, indicating robust signs of durability. The dosing of the first Australian patient represents an important step in assessing the therapy's broader clinical applicability and potential benefits for patients with advanced lymphoma.
![已发布版本的引用 (APA)：Klerx, M., Morren, J., & Slootweg, H. (2019)。分析影响低压电缆电网可靠性的参数及其在资产管理中的适用性。IEEE Transactions on Power Delivery，34(4)，1432-1441。[8663443]。https://doi.org/10.1109/TPWRD.2019.2903928](/simg/g:\will\search\icon\source\5\5eaa1384994dabd84a97bd925b9a1775490005fd.webp)
已发布版本的引用 (APA)：Klerx, M., Morren, J., & Slootweg, H. (2019)。分析影响低压电缆电网可靠性的参数及其在资产管理中的适用性。IEEE Transactions on Power Delivery，34(4)，1432-1441。[8663443]。https://doi.org/10.1109/TPWRD.2019.2903928
摘要 — 配电系统运营商 (DSO) 网络中的大多数中断都发生在低压 (LV) 水平。尽管受影响的客户数量少于中压水平中断，但每年损失的客户时间却相当可观，而且每年解决停电的成本也很高。地下 LV 电缆无法目视检查，监控系统仍处于试验阶段。为了改善 LV 电缆的资产管理 (AM)，DSO 能够使用历史数据结合资产和环境数据进行状况评估是有益的。本文使用 Cox 比例风险模型进行生存分析。该分析的结果可用于识别预测相对较高故障概率的变量并估计电缆的相对故障风险。这可以改进 AM 策略，例如预防性更换电缆。本文提出的方法显示出有希望的结果，可以更深入地了解故障原因。
DODM 5200.45，“原始分类授权机构和撰写安全分类指南”，2025年1月17日
图2。OCA Verification Example .......................................................................................... 12 Figure 3.Process to Determine if Information Can be Classified ............................................... 17 Figure 4.Original Classification Process..................................................................................... 19 Figure 5.Classification Factors to Consider ................................................................................ 20 Figure 6.Example of Core SCG .................................................................................................. 25 Figure 7.Example of Framing Components ................................................................................ 50 Figure 8.Examples of the Use of Framing Components ............................................................. 51 Figure 9.Examples of Mitigation Strategies ............................................................................... 52 Figure 10.Example of an SCG Cover Page ................................................................................ 55 Figure 11.Example of Authority Statement ................................................................................ 56 Figure 12.Examples of Purpose Statement ................................................................................. 56 Figure 13.Examples of Applicability Statement ......................................................................... 57 Figure 14.Example of Classification Challenges Statement ....................................................... 57 Figure 15.Example of OPSEC Statement ................................................................................... 58 Figure 16.Example of Public Release Statement ........................................................................ 58 Figure 17.Example of Foreign Disclosure Statement ................................................................. 58 Figure 18.Examples of Differing Levels of Classification ......................................................... 59 Figure 19.Example of Referencing Other Source or SCG .......................................................... 60 Figure 20.Example of the Use of Enhancement Statements ....................................................... 61 Figure 21.Example of Data in Proper SCG Format .................................................................... 61 Figure 22.Examples of Classification by Compilation in an SCG ............................................. 62 Figure 23.建议的临时分类指南的建议格式................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 63
用于生物医学应用的平板显示技术
Organ-on-Chips (OoCs) have emerged as a human-specific experimental platform for preclinical research and therapeutics testing that will reduce the cost of pre-clinical drug development, provide better physiological relevance and replace animal testing.Yet, the lack of standardization and cost-effective fabrication technologies can hamper wide-spread adoption of OoCs.In this work we validate the use of flat panel display (FPD) tech nology as an enabling and cost-effective technology platform for biomedical applications by demonstrating facile integration of key OoC modules like microfluidics and micro electrode arrays (MEAs) in the standardized 96-well plate format.Individual and integrated modules were tested for their biological applicability in OoCs.For microelectrode arrays we demonstrate 90 – 95% confluency, 3 days after cell seeding and > 70% of the initial mitochondrial cell activity for microfluidic devices.Thus highlighting the biocompatibility of these modules fabricated using FPD technology.Furthermore, we provide two examples of monolithically integrated micro fluidics and microelectronics, i.e.integrated electronic valves and integrated MEAs, that showcase the strength of FPD technology applied to biomedical device fabrication.Finally, the merits and opportunities provided by FPD technology are discussed through examples of advanced structures and functionalities that are unique to this enabling platform.
开发申请5
Executive Summary ................................................................................................................................. 5 1.BRE Project Overview ...................................................................................................................... 8 1.1 Structure of Development Applications for the BRE ...................................................................... 8 2.Project Details ................................................................................................................................... 9 2.1 Project Team................................................................................................................................... 9 2.2 Land Description ............................................................................................................................. 9 3.Engagement ..................................................................................................................................... 15 5.4 .......................................................................... 27 6.8 City of Armadale Local Planning Policies ..................................................................................... 28 6.9 Armadale Activity Centre Plan (City of Armadale) and Armadale City Centre West of Railways Activity Centre Plan (DevelopmentWA) ...................................................................................... 29 7.Conclusion ....................................................................................................................................... 30Site Context ..................................................................................................................................... 10 3.1 Armadale Town Centre................................................................................................................. 10 3.2 Principal Shared Path and DA 5 ................................................................................................... 10 3.3 Planning Approval Applicability .................................................................................................... 11 3.3.1 Planning and Development Act 2005 and Public Works ..................................................... 11 3.3.2 Metropolitan Region Scheme ............................................................................................... 11 3.3.3 Planning Control Area 164 ................................................................................................... 12 3.3.4 METRONET Act ................................................................................................................... 12 3.3.5 BRE Exemption Matrix ......................................................................................................... 13 4.规划框架考虑............................................................................................................................................................................................................................................................................................................................................................................................................................... ....................................................................................................... 24 6.4 State Planning Policy 7.0 – Design of the Built Environment ...................................................... 25 6.5 Development Control Policy 1.6 – Planning to Support Transit use and Development .............. 27 6.6 City of Armadale Local Planning Strategy.................................................................................... 27 6.7 City of Armadale Town Planning Scheme No.
TB-2007-农业建筑物 - pdf
代码生效日期：2020年5月12日1来源文件：19NYCRR 1221 - 建筑物建设19NYCRR 1225 - 防火1225 - 19NYCRR 1226 - 物业维护2主题2主题：适用于农业建筑物和该文件的代码规定，该文件是由国家和市场征询范围的国家和市场的范围征服量的量身部，并在农业和市场上咨询的范围（独立范围）。农业建筑。该文件并未解决与统一代码适用于农业建筑的所有问题。相反，它专注于一些最常见的问题和误解的规定。它作为代码执法人员和农业社区的指导。本文档并非旨在涵盖所有方案或用途。需要单独评估对每个建筑物或使用的统一代码的适用性。
如何引用本文：
市政当局将按照宪法规定（MPOFU＆HLATYWAWAYO 2020; ZWENI; ZWENI，YAN＆UYS 2022）公平，透明，竞争和成本效益开发和实施供应链管理（SCM）系统。供应链管理可能被认为是处理产品的整个生产过程，以最大程度地提高客户体验，质量交付和盈利能力（Hugo，Badenhorst-Weiss＆van Biljon 2021）。它促进了产品，资金和信息的平稳流动，从原材料的采购到将最终产品交付给客户或市场（Qrunfleh＆Tarafdar 2014）。However, the public sector SCM system in South Africa is complex because it involves numerous factors such as several relevant pieces of legislation, numerous stakeholders, different SCM standards, its applicability to public sector organisations that perform various roles, e.g., government departments, state-owned enterprises and municipalities and the scarcity of SCM skills in the country, among others (Ambe & Badenhorst-Weiss 2020; Van der Waldt & Fourie 2022）。这种复杂性会阻碍服务交付，从而为满足各种利益相关者的需求和要求做出不利的贡献。
FSIMS 飞行标准信息管理系统...
16-1-1-9 适用性和授权标准。UAS 操作的适用性和授权取决于操作是民用、公共还是模型飞机（第 101 部分），以及 UAS 操作是否在美国领空内（美国本土、阿拉斯加、夏威夷、美国领土和美国领海上方的空域）。根据国际法，在美国领空之外的 UAS 操作将归类为国家或民用操作。