IN THE NEWS Vasken Dilsizian, MD appeared in numerous media outlets: “Local Cancer Research and Treatment Initiatives”, FOX-5 (WTTG-TV), Washington, DC, http://ow.ly/lhhj50Ms RyQ “Doctor Explains Ways Nuclear Medicine Can Fight Cancer”, NBC Bay Area (KNTV-TV) news, San Francisco, CA https://www.nbcbayarea.c om/news/news/hews/watch- doctor-explains-ways-ways-核 - 米医学 - 尼斯 - 搏斗 - 搏击 - cancer/3140326“防止压力:对您的心脏的影响” CBS-DC(WUSA-TV),华盛顿 - TV),华盛顿州,华盛顿,DC HTTPS:// /5581BC26-3307-42E0-AB6C-18DE28CAD418“压力如何影响您的心脏健康” Fox- 5 dc(WTTG-TV),华盛顿,DC https:///www.fox5dc.fox5dc.co m/why why whate at o a at a a a a i at o a a i at o a a a i at a a a a i ITS的使用工具斯克里普斯新闻报道。在YouTube上看到它。
Controlling microstructure in fusion-based metal additive manufacturing (AM) remains a challenge due to numerous parameters directly impacting solidification conditions. Multiprincipal element alloys (MPEAs) offer a vast compositional design space for microstructural engineering due to their chemical complexity and exceptional properties. Here, we establish a novel alloy design paradigm in MPEAs for AM using the FeMnCoCr system. By exploiting the decreasing phase stability with increasing Mn content, we achieve notable grain refinement and breakdown of columnar grain growth. We combine thermodynamic modeling, operando synchrotron X-ray diffraction, multiscale microstructural characterization, and mechanical testing to gain insight into the solidification physics and its ramifications on the resulting microstructure. This work paves way for tailoring grain sizes through targeted manipulation of phase stability, thereby advancing microstructure control in AM.
纽约市环境保护部(DEP)在建立长期计划的传统的同时,继续进行创新的研究。我们对未来的持续关注反映在供水局(BWS)内进行的广泛研究中。一种转型方法对于应对不断变化的监管景观和供水运营挑战至关重要。这个2024-2025 BWS研究议程为未来几年的研究提供了一个框架和背景。As we look to the future, there are numerous factors influencing the bureau's near-term research: the United States Environmental Protection Agency's (EPA) Proposed Lead and Copper Rule Improvements (LCRI), the EPA's six-year review of microbial and disinfection byproduct rules, ongoing analysis on the effects of climate change, the proliferation of invasive species, taste and odor, and recent New York State and federal proposals regarding多氟烷基物质,所有这些都指导该局的优先事项。
该报告的早期草案是由太阳能技术顾问(STA)的Jorge Servert,JoséManuelNieto和DiegoLópez编写的。由Erik Fernstrom(世界银行)主持的专家小组对此报告进行了彻底审查,其中包括Pierre Audinet(世界银行),Luis Crespo(欧洲太阳能热电协会),CédricPhilibert(然后是国际能源机构)和Dana Younger(然后在IFC)。响应该小组的反馈,与Pablo Ralon(Irena)和Michael Taylor(Irena)合作制作了新草案。World Bank Group staff and consultants contributed in numerous ways, and included: Zuzana Dobrotková, Gabriela Elizondo Azuela, Therese Fernlund, Chris Edward Jackson, Vanessa Janik, Elisabeth Maier, Angeline Mani, Manuel Millan Sanchez, Deger Saygin, Yanqin Song, Nadia Taobane, Efstratios Tavoulareas, Dana Younger, Alexis Gazzo,Christoph Kost,Silvia Pariente-David,Jonathan Walters和Frank Wouters。
地理位置加权的随机森林(GRF)是一种空间分析方法,它适合随机森林算法的局部范围,用于研究空间非平稳性,在依赖性变量和一组自变量之间的关系中。可以考虑到相邻的观测值,可以通过为空间中的每个观测值拟合子模型来实现后者。这项技术采用了地理位置加权回归的想法,Kalogirou(2003)。它以灵活的非线性方法对非平稳性进行建模,从而弥合机器学习和地理模型之间的差距。The main difference between a tradition (linear) GWR and GRF is that we can model non-stationarity coupled with a flexible non-linear model which is very hard to overfit due to its bootstrapping nature, thus relaxing the assumptions of traditional Gaussian statistics.GRF is suitable for datasets with numerous predictors due to the robustness of the random forest algo- rithm in high dimensionality.
2022年的《水平减少法》(IRA)和2021年的基础设施投资和就业法案,通常称为两党基础设施法(BIL),共同代表了美国联邦政府在美国能源系统现代化和脱碳中投资的最大承诺。国会预算(CBO)估计,从2022年到2031年,对两项法律授权的广泛气候和清洁能源计划,税收抵免和其他激励措施的全部支持将超过4300亿美元(CRS 2022; CBO 2021,2022)。While the climate and clean energy provisions are numerous and have the potential to impact all aspects of the U.S. energy system from fuel and electricity production to final consumption in industry, transportation, and buildings, the provisions relevant to the electricity sector—in particular the suite of tax credits for clean generation, storage, and carbon dioxide (CO 2 ) capture and storage—are expected to be some of the most consequential in terms of emissions reduction and clean energy deployment (Larsen等人2022;詹金斯,梅菲尔德等。2022; Mahajan等。2022; Zhao等。2022)。
Matthew Minson,医学博士是El Dorado县的卫生官员。 An award- winning, best-selling author and inventor, he has a storied career in clinical medicine and public service including holding positions at the local (Texas and now California) state (Maryland and Texas) and the federal level (Health and Human Services) with numerous commendations including a secretariat's commendation and award for leading the creation of the National Health Security Strategy, Federal and State awards for emergency and disaster response, and for serving as the Deputy Coordinator for the美国政府对海地地震的反应。 此外,他拥有漫长的部署投资组合,包括零地面,哥伦比亚航天飞机恢复和卡特里娜飓风,丽塔等。 作为USAR和NDMS医师,他还获得了证书,为 - 迅速的水救援,危险品和一项受限制的太空技术,并曾在FEMA IST和联邦医学专家教练中任职。 他是国防医学准备培训研究所的毕业生,他是NFPA委员会的主要成员,涉及第一响应者标准和保护措施,并且一直是Beio,Chem和Responder Protections的白宫联络人,也是联邦资格的健康中心医疗总监。 他在山谷健康委员会任职,并与他的出色妻子,两只有时是边缘狗和一只难以捉摸的猫一起居住在埃尔多拉多县。Matthew Minson,医学博士是El Dorado县的卫生官员。An award- winning, best-selling author and inventor, he has a storied career in clinical medicine and public service including holding positions at the local (Texas and now California) state (Maryland and Texas) and the federal level (Health and Human Services) with numerous commendations including a secretariat's commendation and award for leading the creation of the National Health Security Strategy, Federal and State awards for emergency and disaster response, and for serving as the Deputy Coordinator for the美国政府对海地地震的反应。此外,他拥有漫长的部署投资组合,包括零地面,哥伦比亚航天飞机恢复和卡特里娜飓风,丽塔等。作为USAR和NDMS医师,他还获得了证书,为 - 迅速的水救援,危险品和一项受限制的太空技术,并曾在FEMA IST和联邦医学专家教练中任职。他是国防医学准备培训研究所的毕业生,他是NFPA委员会的主要成员,涉及第一响应者标准和保护措施,并且一直是Beio,Chem和Responder Protections的白宫联络人,也是联邦资格的健康中心医疗总监。他在山谷健康委员会任职,并与他的出色妻子,两只有时是边缘狗和一只难以捉摸的猫一起居住在埃尔多拉多县。
Natural products from Actinobacteria,Hsi commonly known as actinomycetes, have historically provided humans with numerous antibiotics (e.g., streptomycin, gentamicin, and vancomycin) ( Schatz et al., 1944 ; Cooper and Yudis, 1967 ; Rake et al., 1986 ), anticancer agents (e.g., doxorubicin, bleomycin, and Calicheamicins(Shastri等,1971; Maiese等,1989)和Agrochemicals(例如Avermectin和pinosad)(West,1996; Molinari et al。,2010)。应强调,所有认可的抗生素中约有三分之二来自放线菌,主要由链霉菌物种衍生出来,强调了这些微生物的重要性(Barka等,2016)。从放线菌对新天然产物的发现和生物学评估是后基因组时代的无尽领域,主要是由微生物基因组学和合成生物学的进步驱动。了解放线菌天然产物的生物合成不仅阐明了自然如何从小型构件(例如氨基酸和酰基-COA)中构建这些复杂分子,而且还为提高工业发展的产量提供了基础。一些天然产品具有前所未有的结构支架和令人印象深刻的生物学活动,激发了合成和药物化学家设计和综合药物的下一代。此外,放线菌具有通过发酵技术实现天然产物的优势。
This report benefits from the reviews and comments of numerous experts, including Pietro Altermatt (Trina Solar), Alex Barrows (exa-watt), Volker Berkhout (Fraunhofer Institute for Energy Economics and Energy System Technology), Marcel Bial (European Solar Thermal Electricity Association (ESTELA)), Matteo Bianciotto (IHA), Rina Bohle Zeller (VESTAS), Christian Breyer (LUT), Alex Campbell (IHA), Guiseppe Casubolo (SQM), Jürgen Dersch (DLR), Alain Dollet (CNRS / PROMES), Rebecca Ellis (IHA), Gilles Flamant (PROMES-CNRS), Jérémie Geelen (Bioenergy Europe), Konstantinos Genikomsakis (ESTELA), Paul Komor (University of Colorado at Boulder), Eric Lantz (NREL/IEA Wind Task 26), Joyce Lee (GWEC), Jon Lezamiz Cortazar (Siemens Gamesa), Elvira Lopez Prados (Acciona), Angelica Marsico(ESTELA)、Gonzalo Martin(Protermosolar)、David Moser(Eurac Research)、Stefan Nowak(NET)、Werner Platzer(Fraunhofer ISE)、Manuel Quero(Sunntics)、Christoph Richter(DLR / SolarPACES)、Santa Rostoka(ESTELA)、Ricardo Sanchez(PSA)、Eero Vartiainen(Fortum Renewables Oy)、Yuetao Xie(CREEI)、Feng Zhao(GWEC)。所有观点和错误仍属于作者。
语言要么与奥澳属,印度欧洲,德拉维语和跨性别的希马拉亚语言家庭一起使用,要么代表语言隔离株。在最广泛的地理术语中,印度部落倾向于分类为南部,北部,东部和西部部落人口。在语言,生活方式和社会习俗方面,每个种族部落人口都是独一无二的。Studies have demonstrated that the populace of the Indian subcontinent is comprised of numerous small endogamous populations as a consequence of strict endogamy and social customs, resulting in the great complexity observed in the genetics of Indian populations ( Cordaux et al., 2003 ; 2004 ; Thangaraj et al., 2005 ; 2006 ; Thanseem et al., 2006 ; Basu et al., 2016 ; Mustak et al., 2019)。几项研究强调,由于创始人的效果,隐性疾病在印度人群中表现出来(例如Reich等,2009)。南部部落有一个有趣的母体单倍型分布模式,一些部落显示出非常高的印度特殊单倍群的频率,而其他部落则显示了西欧亚人单倍型的频率较高(印度人类学调查,2021a)。科拉加部落属于后一组。