These tools leverage vast databases of academic citations and metadata, typically relying on large, open scholarly da- tabases and services such as OpenAlex (a free, open source index of scholarly works for the scientific community), Se- mantic Scholar (an AI-powered search engine for academic papers using machine learning to identify connections be- tween works), and Crossref (a service that provides DOIs for academic content, enabling persistent links to research输出)。这些特征包括基于Web的Interfaces连接到开放引用数据库和知识图,基于用户选择的种子论文的起点,基于引用的算法,用于推荐相关论文,连接的交互式可视化以及需要的连接过程以及用于精炼和ex-ex-ex-ex-panding panding文献MAPS MAPS MAPS MAPS。
• Two main types of DRI processes: Gas-based DRI and Coal-based DRI • Iron ore pellets, typically containing a mixture of iron oxide and other elements are prepared • Iron ore pellets undergo chemical reactions with reducing agent (natural gas or carbon from coal), resulting in the removal of oxygen to produce direct reduced iron in the lower part of the shaft • The DRI along with scrap steel, is then charged into the Electric Arc炉子•电力用于产生电弧,该电弧融化炉子中的DRI和废料钢•添加合金或其他添加剂以实现所需的钢组成•由于将化石能源用作还原剂和非可再生电力•目前通过Dri
the voltage difference (ΔE) is 0.348 V. The Ni 2+ /Ni 4+ anodic and cathodic peaks of the Mo/F-2 sample correspond to 4.879 V and 4.578 V, respectively, and the ΔE value is 0.301 V. Typically, the potential difference (ΔE) between the anode peak and the cathode peak reflects the electrochemical polarization [47].MO/F-2样品的ΔE值小于原始样品,表明MO/F-2样品中的锂插入/提取动力学更快。结果与上述速率性能测试结果一致,表明适当量的MO-F共同掺杂可以帮助减少极化,从而提高LNMO材料的速率能力。
黑色素瘤占所有皮肤癌以及美国所有癌症死亡的不到2%。但是,黑色素瘤可能会迅速扩散。因此,早期诊断和治疗对于提高治愈率很重要。局部黑色素瘤的5年生存率为99.6%,区域差异为73.9%,远处转移的生存率为35.1%。Advanced melanoma, also known as unresectable or metastatic disease, are typically treated with immunotherapy with immune checkpoint inhibitors (e.g., ipilimumab, cemiplimab, nivolumab, pembrolizumab) and, if BRAF V600 mutation positive, a BRAF inhibitor (e.g., encorafenib, vemurafenib, dabrafenib) with or without a MEK抑制剂(例如Trametinib,cobimetinib,Binimetinib)。免疫疗法的初始缓解率约为45%,复发率为10%,而BRAF/MEK抑制剂有效地收缩了肿瘤,但由于抗性而导致的复发率较高。对于持续进行性疾病,化学疗法是一种选择,但它表现出有限的反应率为4%至10%,中位总生存率约为7个月。
Abstract: Information located in an entanglement island in semiclassical gravity can be nonperturbatively reconstructed from distant radiation, implying a radical breakdown of effective field theory. We show that this occurs well outside of the black hole stretched horizon. We compute the island associated to large-angular momentum Hawking modes of a four- dimensional Schwarzschild black hole. These modes typically fall back into the black hole but can be extracted to infinity by relativistic strings or, more abstractly, by asymptotic boundary operators constructed using the timelike tube theorem. Remarkably, we find that their island can protrude a distance of order p ℓ p r hor outside the horizon. This is parametrically larger than the Planck scale ℓ p and is comparable to the Bohr radius for supermassive black holes. Therefore, in principle, a distant observer can determine experimentally whether the black hole information paradox is resolved by complementarity, or by a firewall.
2.1。大B细胞淋巴瘤(LBCL)是非霍奇金淋巴瘤的侵袭性亚型,其中DLBCL是最常见的。每年在新加坡诊断出大约300例DLBCL患者。尽管许多患者可以用一线多药免疫化学疗法治愈,但经历了30-40%的经验复发或患有原发性难治性疾病,需要进一步治疗。2.2。In local practice, patients with relapsed or refractory DLBCL are typically treated with salvage chemotherapy at the third-line setting, using treatments such as R-DHAP (rituximab, dexamethasone, cisplatin, cytarabine), R-GDP (rituximab, gemcitabine, dexamethasone, cisplatin or carboplatin), and R-ICE (利妥昔单抗,ifosfomide,carboplatin,epoposide)。2.3。tisagenlecleucel是一种一次性的嵌合抗原受体T细胞(CAR-T)治疗。委员会承认临床需要考虑tisagenlecleucel进行资金,以提高负担能力并确保适当的患者护理。
When using glycidyl azide binders in propellants, the chemist typically face the following challenges: ‒ insufficient mechanical properties, ‒ high glass transition temperature (cured GAP binder ~ ‒35 °C), ‒ filler-binder interactions, ‒ high mixing and casting viscosities during processing, which limits the maximum filler content, ‒ low reactivity during curing due to the secondary hydroxyl如果在配方中存在水的痕迹,可能会导致侧反应的组,并且当使用与一级羟基的链条扩展/交联三一个时,也有问题的固化, - 极性粘合剂中能量填充物的溶解度, - 价格。主要挑战之一是实现推进剂的良好机械性能。火箭推进剂的机械性能由粘合剂网络,填充物和粘合剂/填充物相互作用确定。
前瞻性陈述本公司责任报告中提供的信息(“报告”)包括旨在根据我们当前的观点和假设来表达预期结果的前瞻性陈述。结果,这些前瞻性陈述受到许多风险,不确定性以及未来事件的结果,这些风险可能会导致实际结果,绩效或成就,从而与本报告中表达,预测或暗示的结果有重大不同。Forward-looking statements are typically identified by using words such as “may,” “believe,” “expect,” “anticipate,” “intend,” “estimate,” “project,” “target,” “goal,” “plan,” “should,” “will,” “predict,” “potential,” “strategy” and similar expressions that convey the uncertainty of future events or the unpredictability of outcomes.这些前瞻性陈述包括但不限于我们所采取的未来行动,管理计划,目标和目标,未来的支出,公司结构以及收购和处置策略。
结果:该研究对全球队列中HPDL相关的神经退行性疾病的自然历史进行了定量模拟,从而阐明了该疾病的分子和表型谱系,并鉴定出三个不同的患者亚组,其特征在于,以临床表型,发育轨迹和存活率的临床表型,临床表型,发育型和存活率的年龄差异显着差异。It also establishes genotype-phenotype associations, finding that presence of a predicted moderately pathogenic missense variant in at least one allele typically leads to a milder, predominantly spastic paraplegic phenotype (OR = 12.4, p < 0.0001) with later disease onset (11 years [IQR = 11] vs. 6 months [IQR = 11], p < 0.0001), whereas双重,高度致病的错义或蛋白质截断的变体与更严重的表型和预期寿命降低有关(中位生存期= 11.0岁)。
An Integrated Research Project (IRP) is an intensive, faculty-led, student-executed research effort. It places faculty and students from across the US Army War College (USAWC) in a team setting that produces scholarship of value to the Army, the Joint Force and/or the Department of Defense (DoD). Students can directly influence Army policy, inform senior leader decision-making, and contribute scholarship of value to the national security community beyond the scale and impact typically possible with a Strategic Research Requirement (SRR). Every IRP has at least one external sponsor that establishes the research requirement and/or has a vested interest in the topic. A sponsor is an external entity that agrees to assist USAWC research, sometimes with financial or materiel means but frequently through expert advice or feedback to the research effort. Students should sign up for an IRP only after meeting with IRP faculty leads and after considering the full menu of enrichment programs and other activities. Students may be required to travel to support