XiaoMi-AI文件搜索系统
World File Search Systemfocusing
认知科学
Cognitive science is the study of the human mind and brain, focusing on how the mind represents and manipulates knowledge and how mental representations and processes are realized in the brain. Conceiving of the mind as an abstract computing device instantiated in the brain, cognitive scientists endeavor to understand the mental computations underlying cognitive functioning and how these computations are implemented by neural tissue. Cognitive science has emerged at the interface of several disciplines. Central among these are cognitive psychology, linguistics, and portions of computer science and artificial intelligence; other important components derive from work in the neurosciences, philosophy, and anthropology. This diverse ancestry has brought into cognitive science several different perspectives and methodologies. Cognitive scientists endeavor to unite such varieties of perspectives around the central goal of characterizing the structure of human intellectual functioning. It is this common object of inquiry that integrates traditionally separate disciplines into the unified field of cognitive science.
调查机器学习和自然语言处理技术用于检测饮食失调：系统文献评论
自然语言处理（NLP）和机器学习（ML）领域的最新发展已显示自动文本处理的显着改进。同时，人类语言的表达在发现心理健康问题中起着核心作用。虽然口语在接受患者的访谈中被隐式评估，但书面语言也可以为临床专业人员提供有趣的见解。现有的工作中经常研究心理健康问题，例如抑郁或焦虑。然而，还在研究饮食失调的诊断如何从这些新技术中受益。在本文中，我们介绍了该领域最新研究的系统概述。Our investigation encompasses four key areas: (a) an analysis of the metadata from published papers, (b) an examination of the sizes and speci fi c topics of the datasets employed, (c) a review of the application of machine learning techniques in detecting eating disorders from text, and fi nally (d) an evaluation of the models used, focusing on their performance, limitations, and the potential risks associated with current methodologies.
代谢破坏肠中的化学物质
尽管内分泌破坏者的概念首次出现在大约30年前，但这些物质在代谢病理学（肥胖，糖尿病，肝脂肪变性等）的病因学中相对较新的参与。引起了代谢破坏化学物质（MDC）的概念。在这些物质的代谢中断的背景下，已经对肝脏和脂肪组织等器官进行了很好的研究。但是，尽管与这些器官的密切联系，但肠道一直没有探索。体内模型可用于研究MDC在静脉内的影响，此外，还可以研究与其他生物体的相互作用。在后者的方面，斑马鱼是一种动物模型，它越来越多地用于表征内分泌干扰物及其用作评估对肠道影响的模型，毫无疑问，毫无疑问，它会扩大。This review aims to highlight the importance of the intestine in metabolism and present the zebrafish as a relevant alternative model for investigating the effect of pollutants in the intestine by focusing, in particular, on cyto- chrome P450 3A (CYP3A), one of the major molecular players in endoge- nous and MDCs metabolism in the gut.
Dolphicam 2产品规格
软件DolphICAM2软件将每个传感器元素的数据实时组合到超声图像中。除了来自单个传感器元素的信号外，该软件还可以通过所检查的材料可视化垂直和水平横截面和3D视图。现代直观的用户界面使得从Dolphicam2开始变得容易。同时，高级功能（例如FIR滤波器和Total Focusing方法）可以帮助经验丰富的用户检测和分类最佳的材料功能。开放的，记录的数据文件格式允许用户将其数据集导出到例如matlab，或保存以备将来参考。有或没有编码器指导的有或没有编码器指导的缝制模式，可以轻松检查更大的区域，并且报告功能可以轻松保存特别感兴趣的图像并将它们组合到Microsoft Word文档中。最后但并非最不重要的一点是，在常规DolphICAM2应用程序不是正确的解决方案的情况下，多平台DolphICAM2 SDK可用于从DolphICAM2中控制和获取数据。
Prosperity Widely Shared: The Oregon State Plan
• Our track record of educating a skilled workforce, in person and online. The three goals of this plan are interdependent. We must rally around them all to be successful. Our research ambitions will be achieved with new revenues from a fully realized educational mission, one defined by improved outcomes and expanded online education. Our ability to drive economic development requires producing an educated workforce as well as creating human-centered, sustainable solutions that emerge from big discoveries. Achieving our goals in the Believe It! Campaign will also help fuel our success. Our plan is rooted in pragmatic, scalable problem-solving; powered by our belief in a bright future; and driven by the moral imperative of civic contribution rather than institutional self-preservation. By focusing on excellence and impacts in all we do—and open to new ways of thinking and doing— we will deliver on the promise of our public mission and reward the public's trust by proving what public research universities can achieve.
在微生物组中微生物裂解中的遗传潜能与代谢调节和表达之间的解耦
抽象的宏基因组学，元文字组学和元蛋白质组学用于探索酶分泌的微生物能力，但是在生态系统中，pro tein te-tein编码基因与相应的转录本/蛋白之间的联系是毫无疑问的。By conducting a multi-omics comparison focusing on key enzymes (carbohydrate-active enzymes [CAZymes] and peptidases) cleaving the main biomole cules across distinct microbiomes living in the ocean, soil, and human gut, we show that the community structure, functional diversity, and secretion mechanisms of microbial secretory CAZymes and peptidases vary drastically between微生物组在主质，元文字和元蛋白质组水平上。由于主要参与者对有机物物质源和浓度的不同反应，这种变化导致cazymes与肽酶之间从遗传潜能到蛋白质表达的decouper质关系。我们的结果强调了对有机物上微生物裂解的因素进行系统分析的需求，以更好地将OMICS数据与生态系统过程联系起来。
健康与疾病中的乳酸化
乳酸是各种细胞生理功能中必不可少的物质，在能量代谢和信号转导的不同方面扮演调节作用。lactylation（KLA）是一种乳酸发挥其功能的关键途径，已被鉴定为一种新型的翻译后修饰（PTM）。研究表明，KLA是多种生物的基本平衡机制，并且通过不同的途径参与了许多关键的细胞生物过程。KLA与疾病的发展密切相关，代表了潜在且重要的新药靶标。 与现有报告一致，我们在组蛋白和非组蛋白上搜索了新发现的KLA位点。 reviewed the regulatory mechanisms of Kla (particularly focusing on the enzymes directly involved in the reversible regulation of Kla, including “writers” (modifying enzymes), “readers” (modification-binding enzymes), and “erasers” (demodifying enzymes); and summarized the crosstalk between different PTMs to help researchers better understand the widespread distribution of Kla and its各种功能 此外，考虑到KLA在生理和病理环境中的“双刃剑”作用，该评论突出了KLA在生理状态中的“有益”生物学功能（能量代谢，炎症反应，细胞命运，开发，发育等） 及其对病理过程的“有害”致病性或诱导作用，尤其是恶性肿瘤和复杂的非肿瘤疾病。 我们还阐明了健康和疾病中KLA的分子机制，并讨论了其作为治疗靶点的可行性。KLA与疾病的发展密切相关，代表了潜在且重要的新药靶标。与现有报告一致，我们在组蛋白和非组蛋白上搜索了新发现的KLA位点。 reviewed the regulatory mechanisms of Kla (particularly focusing on the enzymes directly involved in the reversible regulation of Kla, including “writers” (modifying enzymes), “readers” (modification-binding enzymes), and “erasers” (demodifying enzymes); and summarized the crosstalk between different PTMs to help researchers better understand the widespread distribution of Kla and its各种功能此外，考虑到KLA在生理和病理环境中的“双刃剑”作用，该评论突出了KLA在生理状态中的“有益”生物学功能（能量代谢，炎症反应，细胞命运，开发，发育等）及其对病理过程的“有害”致病性或诱导作用，尤其是恶性肿瘤和复杂的非肿瘤疾病。我们还阐明了健康和疾病中KLA的分子机制，并讨论了其作为治疗靶点的可行性。最后，我们描述了KLA的检测技术及其在诊断和临床环境中的潜在应用，旨在为治疗各种疾病的治疗提供新的见解，并加速从实验室研究到临床实践的翻译。
![水产养殖计划的博士学位候选人在一个为期4年的资助项目中从事鱼类营养和健康的工作。 [参考。 CPI3624] IRTA目前正在寻求](/simg/5\5b9671159d396e04c645e1e35ee7ac54733ce638.webp)
水产养殖计划的博士学位候选人在一个为期4年的资助项目中从事鱼类营养和健康的工作。 [参考。 CPI3624] IRTA目前正在寻求
水产养殖计划的博士学位候选人在一个为期4年的资助项目中从事鱼类营养和健康的工作。[参考。CPI3624] IRTA目前正在寻求一个热情而有动力的博士候选人加入水产养殖计划。 We invite applications from ambitious candidates with relevant research experience and passion to conduct research and innovation activities on aquaculture with a special focus on fish nutrition and health within the funded project entitled NUTRITIONAL STRATEGIES TO MITIGATE THE EFFECTS OF CLIMATE CHANGE ON RELEVANT AQUACULTURE FISH SPECIES: FOCUSING ON MUCOSAL HEALTH AND STRESS RESPONSE (reference number PID2023-147976OR-C21; Agencia Estatal de西班牙调查）。 该项目的目标是测试，验证和描述不同营养策略的作用方式，以应对两种养殖鱼类的热浪。 研究方法将基于测试不同的饮食配方和饲料添加剂，并在将鱼暴露于生物（细菌病）和非生物（水温和缺氧）时测试其性能，并了解其对宿主的压力和免疫再生的作用方式，GUT Microbobiota和相关的生理学过程。 实现项目目标将支持更具弹性和可持续的水产养殖。 该项目与巴塞罗那大学的A. Ibarz教授合作（鱼类研究小组的非侵入性生物指导者-Nibifish）CPI3624] IRTA目前正在寻求一个热情而有动力的博士候选人加入水产养殖计划。We invite applications from ambitious candidates with relevant research experience and passion to conduct research and innovation activities on aquaculture with a special focus on fish nutrition and health within the funded project entitled NUTRITIONAL STRATEGIES TO MITIGATE THE EFFECTS OF CLIMATE CHANGE ON RELEVANT AQUACULTURE FISH SPECIES: FOCUSING ON MUCOSAL HEALTH AND STRESS RESPONSE (reference number PID2023-147976OR-C21; Agencia Estatal de西班牙调查）。该项目的目标是测试，验证和描述不同营养策略的作用方式，以应对两种养殖鱼类的热浪。研究方法将基于测试不同的饮食配方和饲料添加剂，并在将鱼暴露于生物（细菌病）和非生物（水温和缺氧）时测试其性能，并了解其对宿主的压力和免疫再生的作用方式，GUT Microbobiota和相关的生理学过程。实现项目目标将支持更具弹性和可持续的水产养殖。该项目与巴塞罗那大学的A. Ibarz教授合作（鱼类研究小组的非侵入性生物指导者-Nibifish）
