XiaoMi-AI文件搜索系统
World File Search Systeminstance
倡导策略
超越目标3，CVD受到影响，并且可以为每个SDG心脏健康做出贡献，这是一个多部门问题，并与可持续发展目标紧密相关。For instance, fighting CVD and working towards UHC can also contribute to achieving: a reduction in poverty ( SDG 1 ) by protecting people from financial hardship caused by CVD, as well as SDG2 (healthy weight), SDG3 (described above), SDG5 (empowerment among women and girls), SDG8 (increased employment and economic growth and reduced health costs), SDG9 (sustainable基础设施），SDG10，（减少不平等），SDG11（空气质量），SDG12（化石燃料消耗），SDG13（缓解气候变化和环境保护）以及SDG15（环境保护）（环境保护）和SDG17（为更活跃的世界提供了合作伙伴）。
基于机器学习的预测未计划的重新入学，这是由于主要不利
MACHINE LEARNING ALGORITHM • Training set: HCUP data from 2017 to 2018 • Test set: HCUP data in 2019 • Algorithm: Tree-based gradient boost framework (LightGBM) • Feature selection: L1 penalty • Hyperparameter tuning: Learning rate, number of leaves, minimum sum of instance weight (Hessian), frequency of subsample, subsample ratio of columns, L1 penalty, and the scale of positive and negative weight.•首先对超参数进行筛选，并使用贝叶斯搜索进行优化。•不平衡分类：成本敏感的学习•交叉验证：5倍分层的交叉验证•阈值：Youden的J统计量•分类性能指标：平衡精度； F2分数；接收器操作曲线（AUROC）下方； Precision-Recall曲线（AUPRC）下的区域
我们学到多少？测量通过选择与贝叶斯更新的对称和不对称偏差
ilke aydogan：i.aydogan@ieseg.fraurélienbaillon：baillon@em-lyon.com emmanuel kemel：emmanuel.kemel@gemel@greg-hec.com chen li：c.li@ese@ese.eur.nl，我们感谢Peter Wakker和Han Bleichrodt和Han Bleichrodt的帮助和讨论。Baillon承认NWO Vidi Grant 452-13-013的财务支持。Aydogan承认该地区Haut-De-France（2021.00865 Clam）和欧盟的Horizon Horizon Europe Research and Innovation计划，根据Grant协议（101056891具有能力）。li感谢NWO Veni Grant VI.Veni.191E.024的财务支持。1 See, for instance, Phillips and Edwards ( 1966 ), Edwards ( 1968 ), Tversky and Kahneman ( 1974 ), El-Gamal and Grether ( 1995 ), Oswald and Grosjean ( 2004 ), Möbius, Niederle, Niehaus, and Rosenblat ( 2022 ), Bén- abou and Tirole ( 2016 ), Ambuehl and Li ( 2018 ).
将Alphafold的力量放到世界手中
最令人兴奋的是，在世界各地的科学家手中，这款新的蛋白质年鉴将实现和加速研究，这将促进我们对这些生活基础的理解。已经通过我们的早期合作，我们已经看到了研究人员在自己的工作中使用Alphafold的有希望的信号。For instance, the Drugs for Neglected Diseases Initiative (DNDi) has advanced their research into life-saving cures for diseases that disproportionately affect the poorer parts of the world, and the Centre for Enzyme Innovation at the University of Portsmouth (CEI) is using AlphaFold to help engineer faster enzymes for recycling some of our most polluting single-use plastics.对于那些依靠实验蛋白结构确定的科学家来说，Alphafold的预测有助于加速他们的研究。作为另一个例子，科罗拉多大学博尔德大学的一支团队正在寻找使用Alphafold预测来研究抗生素耐药性的希望，而A
Editorial: Predictive and diagnostic approaches for systemic disorders using ocular assessment
Systemic diseases often manifest in the eye due to their unique vasculature and neural composition. The retina, for instance, shares similar embryological origins with the brain and is supplied by a rich vascular network. This makes it an ideal site for detecting vascular and neurological changes that reflect systemic conditions. Conditions such as diabetes, hypertension, and autoimmune diseases frequently display characteristic ocular signs, which, when detected early, can facilitate timely interventions. For example, diabetic retinopathy remains a prominent example of how ophthalmic examinations can reveal the severity and progression of systemic diabetes. Retinal imaging enables the identification of microaneurysms, hemorrhages, and neovascularization, all hallmark features of the disease ( 1 ). The presence of these signs not only confirms the diagnosis but can also predict the potential for systemic complications ( 2 ).
教学术语
Lesson Plan – written instructions for a class session that includes a learning objective, introduction, teacher and student actions, assessments, materials and resources Linguistic Learning -learning style that includes an emphasis in reading and writing to measure standards Logical Learning- learning style in which learning takes place by the students ability to reason, problem solve, and think methodically M Maslow Hierarchy of Needs- Theorist , Abraham Maslow, stated that people prioritize needs and the most basic need is for physical survival before other needs can be met Multiple Intelligences – Howard Gardner's theory which categorizes learner strengths into the following categories: visual/spatial, logical/mathematical, naturalistic, linguistic, bodily/kinesthetic, interpersonal, and intrapersonal Modeling- being an example to follow Modifications (Also in Domain 2) - the act or instance of altering or changing instructional materials and/or strategies, activities and assessments
Executive Summary Report (ESR) - 16U4SBSP
Swarms of CubeSats for kW-scale Space-Based Solar Power (16U4SBSP) Executive Summary Report (ESR) Study Open Space Innovation Platform (OSIP) campaign, “Innovative Mission Concepts Enabled by Swarms of CubeSats” Affiliation(s): Sirin Orbital Systems AG (Prime, CH), Delft University of Technology (Sub 1, NL), University of Strathclyde (Sub 2, UK) Activity summary: The “16U4SBSP” mission concept is a fundamental technology demonstration step for the realization of kW-/MW-/GW-scale Space-Based Solar Power (SBSP) based on flight formation, a distributed or aggregated swarm of small satellites contrary to conventional concepts of monolithic giant SBSP satellites. In this mission, a swarm of 16U CubeSats collaboratively supply wireless power via Radio- Frequency waves to end-users in different locations on the ground, for instance to provide backup power for emergency situations, and also for space-to-space commercial use-cases.
将生物催化与化学分析整合进行选择性转化
可以与级联反应中的酶结合起来，以实现广泛的有趣转换[7 E 9]。For instance, Poelarends and coworkers reported a one- pot cascade synthesis of enantioenriched g -amino- butyric acids (GABA) by combining enantioselective Michael addition catalyzed by an engineered 4- oxalocrotonate tautomerase, aldehyde oxidation cata- lyzed by aldehyde dehydrogenase, and nitro reduction enabled by基于镍的化学还原（图1 A）[7]。这种步进经济学方法提供了高总产率（产量高达70％）和出色的对映选择性（高达98％EE）的药物活性GABA类似物。Greaney，Turner和同事开发了由单胺氧化酶N（MAO-N）组成的兼容的跨脱水耦合过程 - 催化有氧氧化和金介导的C E C键形成，以实现N-Aryl tetrahydroisoquinelines的一盘烷基化[8]。本报告展示了用于C E C键形成的功能组转化的生物催化与过渡金属催化之间的兼容性。
早期的法国数字密码：
路易斯·德·冈萨古（Louis de Gonzague），诺斯公爵（Duk of Nevers）在法国早期的现代历史上发挥了重要作用，尤其是因为他在法国宗教战争期间的政治和外交活动（Boltanski，2006年）。此外，他是16世纪过去二十年来加密实践中的主要参与者之一：数十个手稿（现在保留在BNF）包含了诺斯公爵（Nevers of Nevers）或其中之一的加密信件（BNF，fr。3995）甚至包含68个密码桌。While the letters of the Duke of Nevers are well known to historians (Boltanski, 2006; Le Person, 2002; Le Roux, 2000; Wolfe, 1988), and the majority of these letters has been deciphered as soon as they were received by the recipient (see for instance the interlinear decipherment in the letter from Henri IV to the Duke of Nevers (19 April 1591) at BnF, fr.3615，fol。52），亨利四世给《诺斯公爵》写的一封信在这个语料库中脱颖而出。不仅没有这封信被解密（或者至少没有与信件一起保存其原始解密），而且最重要的是，密码不匹配法国国王的另一个加密信件中使用的密码。
Joseph博士早期Joseph博士早期
·通过多个实例学习国际学习表征会议（ICLR）固有可解释的时间序列分类（2024。·扩展场景到斑点模型：多分辨率的地球观察环境数据科学的多个实例学习（期刊），2023。·一种基于风险的AI监管方法：系统分类和可解释的AI实践脚本：法律，技术与社会杂志，2023年。·通过可解释的多个实例学习神经信息处理系统（Neurips）的轨迹标签的非马尔可奖奖励建模，2022。·用于多个实例学习国际学习表征的不可解释性（ICLR），2022。·场景到点地球观察：通过机器学习（Neurips Workshop）来应对气候变化的多个实例学习，2022年。