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MoA (Mechanism of Action) NXI-101 is tumormicroenvironment (TME) modulator, which - neutralizes the secreted ONCOKINE-1 in TME - activates CD8+ T cells by directly inhibiting MDSC function & recruitment - changes TME from COLD to HOT - blocks tumor's anti-apoptotic signal - synergizes with anti-PD-1 and activates anti-tumor T cell免疫
靶向免疫...
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