3。Global trends in the burden of malaria 22 3.1 Global estimates of malaria cases and deaths, 2000–2020 22 3.2 Estimated malaria cases and deaths in the WHO African Region, 2000–2020 26 3.3 Estimated malaria cases and deaths in the WHO South-East Asia Region, 2000–2020 28 3.4 Estimated malaria cases and deaths in the WHO Eastern Mediterranean Region, 2000–2020 30 3.5 Estimated malaria cases and deaths in the WHO Western Pacific Region, 2000–2020 32 3.6 Estimated malaria cases and deaths in the WHO Region of the Americas, 2000–2020 34 3.7 Estimated malaria cases and deaths in the WHO European Region, 2000–2020 36 3.8 Cases and deaths averted since 2000, globally and by WHO region 36 3.9 Severe malaria: age patterns and phenotypes by transmission intensity 38 3.10怀孕的疟疾负担42