1坎帕尼亚卢吉·范维特利大学高级医学和外科科学系，80138，那不勒斯2 Biology, College of Science and Technology, Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, Philadelphia, PA 19122, USA 5 Division of Cardiology, Department of Medical Translational Sciences, University of Campania Luigi Vanvitelli, 80138 Naples, Italy 6 Independent Researcher, 81024 Maddaloni, Italy 7 Department of Medicine and Health Sciences “Vincenzo Tiberio”, degli Studi del Molise Univers，意大利Campobasso 86100 *通信：alfredo.caturano@unicampania.it;电话。： +39-3338616985†这些作者对这项工作也同样贡献。