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生长激素肽有望延缓衰老——但科学依据如何呢?
舍莫林、替沙莫林和其他生长激素肽被吹捧为抗衰老灵丹妙药,但这些说法背后的证据是什么?
来源:科学美国人这是注射剂时代。 With more than one in 10 Americans now taking GLP-1 weight-loss drugs and some of us branching out to various other peptides, we have as a society seemingly gotten very comfortable with injections that modify our bodies.毕竟,为什么有人不想服用一种可以促进健康恢复、抗衰老、抑制饥饿和促进减肥的药物呢?
这些是注射肽的支持者提出的主张,这些肽有望刺激体内的生长激素水平。但有什么证据呢?我们是否应该尝试生产更多的生长激素?
Growth hormone is a small protein made by the brain’s pituitary gland, and it is released in pulses day and night, explains Brad Anawalt, an endocrinologist at the University of Washington School of Medicine.对于儿童和年轻人,它的作用正如其名称所暗示的那样,可以延长骨骼并帮助身体生长。这种激素的水平在青春期达到顶峰,此后每七到十年就会下降一半。
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在成人中,这种激素在血糖控制、骨密度和肌肉生长方面发挥着作用。但随着年龄的增长,水平大幅下降是生长激素肽背后的全部前提。支持者说,刺激脑下垂体释放更多的生长激素可以抵抗衰老。 Podcaster Andrew Huberman, health coach Christian Poulos and wellness author Mark Hyman are all fans its supposed power over our bodies, to name just a few.
Complicating matters are that two of the most popular growth hormone compounds—sermorelin and tesamorelin—were created with specific people in mind.
