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火灾探测技术的发展
Advancements in data technology, identifiers, and microelectronics, coupled with a deeper understanding of fire physical science, have significantly contributed to significant growth in the fire identification technology over the past decade. In practice, fire identification technology encounters obstacles such as mitigating deceptive issues, increasing responsiveness through dynamic response, and enabling extremely expensive and complex structures to more easily protect the public and comply with evolving regulations. Provision of shields. The purpose of this article is to examine the fluctuations in innovative endeavours within the field of fire identification, such as advancements in sensor architectures, fire data management, and screen technology that incorporate fire recognition frameworks. Our article examines the recent developments in fire identification technology, including emerging sensor, sign, and observation technologies, also unified fire recognition frameworks. A number of the issues that exist in the contemporary fire detection systems are examined, along with the prospective avenues for this research.
生物学
哮喘的特征是气道高反应性（AHR），炎症和重塑。气道平滑肌（ASM）细胞在哮喘的所有这些方面都具有关键作用。ASM细胞的收缩功能主要有助于哮喘患病中的支气管痉挛和可逆气道阻塞。此外，ASM细胞的合成和分泌功能对气道炎症和重塑至关重要。In order to gain a deeper understanding of the role of ASM in all three aspects of asthma pathology—airway hyperreactivity, airway inflammation and remodeling—and to expedite identifying novel, druggable targets related to these aspects, we invite researchers to submit cutting-edge original and review articles on the topic of airway smooth muscle and respiratory diseases.本期特刊旨在为与支气管痉挛（例如哮喘和COPD）相关的有关ASM生物学急需的新知识做出贡献。
当前的人类健康中微生物组研究的进展和挑战：观点
越来越清楚的是，人类微生物群（也称为“隐藏器官”）在维持宿主的生理功能的许多过程中具有关键作用，例如营养萃取，生物活性分子的生物合成，与免疫，内分泌和势能与抗药性相互作用，以及与抗药性相互作用，以及抗癌症的抗性。In the last decade, the development of metagenomic approaches based on the sequencing of the bacterial 16s rRNA gene via Next Generation Sequencing, followed by whole genome sequencing via third generation sequencing technologies, has been one of the great advances in molecular biology, allowing a better pro fi ling of the human microbiota composition and, hence, a deeper understanding of the importance of microbiota in the不同病理学的疗法发生。在这种情况下，为疾病发病机理的人类微生物群的全面表征，以通过操纵微生物群来制定新的潜在治疗或预防策略至关重要。因此，这种观点将集中于微生物组实行和分析的当前和未来技术方法的进度，挑战和承诺。
抽象机制预测深度神经网络中的概括
深度神经网络作品（DNN）的一个长期问题是了解他们令人困惑的概括能力。We approach this prob lem through the unconventional angle of cogni tive abstraction mechanisms , drawing inspiration from recent neuroscience work, allowing us to define the Cognitive Neural Activation metric (CNA) for DNNs, which is the correlation be tween information complexity (entropy) of given input and the concentration of higher activation values in deeper layers of the network.CNA具有高度预测的概括能力，在对近200个网络实例的广泛评估中进行基于规范和偏见的概括指标，其中包括数据集构造组合的广度，尤其是在存在加性噪声的情况下，并且存在/或培训标签被损坏。这些强大的EM PIRICAL结果表明，CNA作为概括度量的有用性，并鼓励对信息复杂性与更深层次网络中的表示之间的联系进行进一步研究，以便更好地了解DNN的概括能力。1
辅助微型铸造支持拓扑保护
刺激靶向神经组织。 [1]它提供了强大的工具，既可以理解脑功能，又可以调节神经回路的活性以改善疾病的预防。 [2]在神经科学研究中使用神经调节已使神经回路中功能连通性的大量发现。 [3–8]此外，能够改善，恢复和替代运动，感觉和认知功能的神经化策略导致了治疗神经精神疾病的典型途径和假肢。 在具有高时空分辨率的深脑区域中对特定细胞类型和神经回路的微创神经调节是神经调节的最终目标[2]，尽管目前的神经调节技术尚未实现。 Here, we focus on how emerging nanotechnology is galva- nizing novel neuromodulation strategies, with an emphasis on recent research progress on nanotechnology-enabled neuro- modulation modalities with less invasive surgical procedures, improved bio-implant interfaces, deeper brain accessibility, and higher spatiotemporal resolution. 我们讨论了纳米技术如何实现特定的神经调节方式，例如电气，光学，化学，声学和磁性，以及使用纳米材料作为能量传感器的跨模式神经调节策略的移植形式。 最后，我们在推进基础研究和临床翻译的神经调节策略方面提供了对未来努力的看法。刺激靶向神经组织。[1]它提供了强大的工具，既可以理解脑功能，又可以调节神经回路的活性以改善疾病的预防。[2]在神经科学研究中使用神经调节已使神经回路中功能连通性的大量发现。[3–8]此外，能够改善，恢复和替代运动，感觉和认知功能的神经化策略导致了治疗神经精神疾病的典型途径和假肢。在具有高时空分辨率的深脑区域中对特定细胞类型和神经回路的微创神经调节是神经调节的最终目标[2]，尽管目前的神经调节技术尚未实现。Here, we focus on how emerging nanotechnology is galva- nizing novel neuromodulation strategies, with an emphasis on recent research progress on nanotechnology-enabled neuro- modulation modalities with less invasive surgical procedures, improved bio-implant interfaces, deeper brain accessibility, and higher spatiotemporal resolution.我们讨论了纳米技术如何实现特定的神经调节方式，例如电气，光学，化学，声学和磁性，以及使用纳米材料作为能量传感器的跨模式神经调节策略的移植形式。最后，我们在推进基础研究和临床翻译的神经调节策略方面提供了对未来努力的看法。
神经标志物发现的质谱 - HAL
摘要：神经退行性疾病是无法治愈的，异质性和依赖年龄的疾病，挑战现代医学。A deeper understanding of the pathogenesis underlying neu- rodegenerative diseases is necessary to solve the unmet need for new diagnostic biomarkers and disease-modifying therapy and reduce these diseases' burden.特定的，翻译后的模式（PTMS）在神经变性中起着重要作用。Due to its proximity to the brain parenchyma, cerebrospinal fluid (CSF) has long been used as an indirect way to measure changes in the brain.质谱法（MS）分析的神经退行性疾病，重点是PTM，在生物标志物发现的背景下，已经改善并打开了场地，用于分析更复杂的矩阵，例如脑组织和血液。值得注意的是，磷酸化的tau蛋白，截短的α-突触核蛋白，APP和TDP -43，以及许多其他修饰，以MS的广泛特征。巨大的潜力是用于临床应用的特定病理PTM签名。本综述着重于参与神经退行性疾病的PTM模型蛋白质，并突出了基于MS的生物标志物发现中最重要和最新的突破。
生物多样性净收益必需品
- 简介和上下文（重要！）- 场景 - 工作的例子和本地化 - 计划委员会和BNG - 更深入的潜水：“重要”的现场增益 - 更深入的潜水：指标？•模板（良好的法律协议）
广告手册和媒体包
• Unrivalled news - Accurate and often exclusive, cross-referenced with international media • Market reports and prices - Daily and weekly market reports that explain what is moving prices and why • Data Dive - A new data journalism offering that delves deeper into larger datasets to analyse the figures, identify the trends, and employ helpful visualisations that deliver compelling news • Resources - A data portal that includes voluntary carbon prices, a carbon project & ratings database, an国际碳交易跟踪器，NDC跟踪器和ETSS世界各地的档案•特别活动 - 我们派遣大型团队来介绍重要的活动。For example, we fielded a 12-person team at UN climate talks (COP29) in Baku, and 5 reported from the biodiversity COP (COP16) in Cali • Newsletters - Our flagship free CP Daily and twice- weekly Biodiversity Pulse • Email alerts - Our subscribers get a CP Alert email when an important story is published • Advertising - Market your products or services to thousands of potential clients via banner advertising • Job listings -在能源，气候变化和生物多样性部门中的角色，无需支付职位空缺或“溢价”促进。•贡献和赞助的内容 - 来自我们的订户，战略合作伙伴和其他领先行业参与者的有见地的帖子
静态和热负载下的帕利行为
f d A value of the picnotropy factor at the asymptotic state boundary surface F m Matsuoa-Nakai factor f s barotropy factor f u collapse potential factor g plastic potential G soil shear modulus G gradient of the soil shear modulus with depth G eff soil effective shear modulus G in soil initial shear modulus G L soil shear modulus at pile tip G L /2 soil shear modulus at pile mid length G m plastic potential for the Mohr-Coulomb model G mech soil mobilized shear modulus G 0 small strain soil shear modulus G 1 soil shear modulus of the shallower layer for two-layer soil G 2 soil shear modulus of the deeper layer for two-layer soil G 90 initial shear stiffness after a 90 ◦ change in the strain path direction h function for the hardening law h Heaviside function h 1 thickness of the shallower layer for two-layer soil H 2厚度的较深层的两层土壤H P硬化模量ˆ
