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当数据涉及三个或多个变量时,将其分类为多变量。这种类型的数据的示例假设广告商希望比较网站上四个广告的普及,然后可以对男性和女性进行点击率,然后可以检查变量之间的关系。它类似于双变量,但包含多个因变量。对此数据进行分析的方法取决于要实现的目标。一些技术是回归分析,路径分析,因子分析和方差多变量分析(MANOVA)。
Ishmail Abdus-Saboor,博士学位副教授,生物科学系首席研究员,Zuckerman Mind Brain Brain Brain Brain Brain Brain Institute Freeman Hrabowski Scholar,Howard Hughes Hughes Medical Institute哥伦比亚大学,3227,百老汇,百老汇3227,百老汇6C,Quad 6c,Quad 6c,纽约州,纽约州,纽约市,纽约市,纽约市,Philadelphia,pennsyia,pennsyia a。1984年5月19日;已婚,两个孩子。教育2006–2012博士细胞和分子生物学,宾夕法尼亚大学(顾问:Meera Sundaram)2002- 2006年B.S.
•使用ctDNA预测黑色素瘤主要研究者对病情疗法的反应:Jessica Cintolo-Gonzalez,MD Lay摘要:黑色素瘤已通过FDA批准的Talimogenelaherparepepvec®(Imlylylylylylylyparpvectecte)通过Incoption(talimygeen)(talimogene laherlyagepvec)进行治疗。这包括每2-3周注射一次。有时由于肿瘤的进展或完整的临床反应而导致的不连续治疗是一个非常明确的决定,导致没有进一步的注射病变,但如果随着时间的流逝,病变的稳定性稳定时,停止注射的决定可能是具有挑战性的。这可能会发生,因为身体检查或射线照相发现并不总是表明存在可行的肿瘤。使用循环肿瘤DNA(CTDNA)监测血液中肿瘤的存在,越来越多地用作预测疾病的存在和对癌症疗法的反应的一种方式。因此,我们认为,测试商业上可用的CTDNA测试(Signateratm),因为它能够反映用TVEC治疗的黑色素瘤患者的存在/不存在可行肿瘤的能力,可以将该平台识别为有价值的工具,可以为这些具有挑战性的治疗决策提供信息。• Determining Patient Outcomes in the Treatment of Mesothelioma with Proteomic Fingerprints Principal Investigators: Brian Cunniff, PhD & Christopher Landry, PhD Lay Summary: The goal of this study is to use proteomics to identify patterns of protein up- and down-regulation in malignant pleural effusion (MPE) fluid of patients diagnosed with mesothelioma.硫代(RSO-021)是一种新的治疗方法,该治疗方法是通过直接给药到胸膜腔(NCT05278975)对1期Mitope试验进行了测试。鉴于间皮瘤从诊断点开始迅速发展,并且在一线和二线治疗后,在早期阶段制定有效的治疗策略很重要。目前,缺乏对影响患者对RSO-021反应的因素的理解。• Impact of environmental toxins on BRPF1 bromodomain acetylated lysine recognition in leukemogenesis Principal Investigator: Karen C. Glass, PhD Lay Summary: Leukemia is a cancer of the blood caused by both genetic and environmental factors that cause the bone marrow cells to grow too rapidly, which interferes with the function of normal red blood cells in transporting oxygen around our body.暴露于有毒物质(即苯和烟草烟雾),农药甚至是土壤中的镍都是患白血病的危险因素。也已知它们会改变我们细胞中对于调节细胞生长很重要的化学信号传导模式。我们建议开发新方法,以识别和表征与这些化学信号结合的蛋白质的相互作用,以确定环境毒素如何改变结合相互作用并促进白血病的发展。
Journal of Materials Chemistry Emerging Investigator Lectureship (Runner-up), 2024 Rising Star in Materials Science, ACS Materials Au, 2023 Camille Dreyfus Teacher-Scholar Award, 2023 Robert A. and Donna B. Paul Award for Excellence in Advising (Cornell), 2021 NSF CAREER Award, 2021 ACS Division of Organic Chemistry Academic Young Investigator, 2021 ACS DIC Award for Undergraduate Research (with Faith Chen), 2020 Scialog Fellow (Negative Emissions Science), 2020 DOE Early Career Award, 2020 NIH Maximizing Investigator's Research Award (MIRA), 2020 ACS PRF Doctoral New Investigator Award, 2019 NIH Ruth L. Kirschstein NRSA Postdoctoral Fellowship, 2016 CERC-WET Fellowship (UC Berkeley), 2016 ACS Division of Organic Chemistry Graduate Fellowship, 2014年(拒绝)杰出教学奖(MIT),2011 NSF研究生研究奖学金,2010年
荣誉和颁奖2017年英国阿伯丁荣誉博士学位学位学位学士学位,2016年2016年杰西·博登·劳埃德(Jessie Boden Lloyd Award 2008 Nijmegen University Center for Infectious Diseases Award 2006 WRO Goslinsgsprijs of the Infectious Diseases Society of the Netherlands 2005 European Society of Clinical Microbiology and Infectious Diseases Young Investigator Award 2003 Postdoctoral Investigator Award, International Cytokine Society 2003 SmithKline Beecham ICAAC Award 2002 International Sepsis Forum Young Investigator Award 2002 Dutch Society for Medical微生物学Aventis奖
This research was conducted by the RIKEN TRIP Initiative, and was conducted by the Japan Society for the Promotion of Science (JSPS) Science Research Funded Funded Research Project (S), "New Generation Magnetic Induction in Magnetic Conductors (Principal Investigator: Tokura Yoshinori, 23H05431)," and the Basic Research (A) "Theoretical Research on Quantum Nonlinear Response (Principal Investigator: Naganaga Naoto, 24H00197)," and the Academic Change Area Research (A) "Theory of Chimeric Quasiparticles (Principal Investigator: Murakami Shuichi, 24H02231)," and the Japan Science and Technology Agency (JST) Strategic Creative Research Promotion Project CREST "Electronic Quantum Phase Control Using Nanospin Structures (Principal Investigator: Naganaga Naoto, JPMJCR1874)"这一事件得到了针对Skyrmion的新拓扑磁科学的支持(主要研究者:U Shuzhen,JPMJCR20T1)。主持人/机构计数器 *请与主持人联系以获取有关研究内容的信息。 Riken研究人员Max T. Birch,基础科学专科研究员,密切相关的量子传导团队,新兴材料科学中心,Riken Research Institute,团队负责人Tokura Yoshinori(东京/东京大学/东京大学教授)
结论:已经开发了一种新型的Tofacitinib LC-MS/MS分析。探索了测量生化依从性的分析的影响。需要进一步的研究,以确定测定的敏感性和测定能力检测不遵守的能力。参考文献:[1] Alten R,KrügerK,Rellecke J,Schiffner-Rohe J,Behmer O,Schiffhorst G等。使用离散选择方法检查患者在类风湿关节炎治疗中的偏好。患者更喜欢依从性。2016; 10:2217-28。 [2] Suzuki M,Tse S,Hirai M,Kurebayashi Y. 将基于生理的药代动力学建模应用于日语预测tofacitinib的预测。 Kobe J Med Sci。 2017; 62(6):E150-E61。 Acknowledgements: Financial support was provided as an Investigator Spon- sored Research Grant from Pfizer Limited Disclosure of Interests: Stephanie Church Grant/research support from: Finan- cial support was provided as an Investigator Sponsored Research Grant from Pfizer Limited, Kimme Hyrich Speakers bureau: Honoraria as a speaker received from Abbvie, Grant/research support from: Financial support was provided as an Investigator Sponsored Research Grant from Pfizer 有限的。 AB在过去的12个月中获得了Scipher Medicine Ltd,Bristol Myers Squibb和Gal-Apagos的赠款。James Bluett Grant/Research Support in:Fanancial Support:Fanancial Support是作为调查员的PFISER LIM-IS提供的调查人员赞助研究赠款。 JB已从UCB,辉瑞和Eli Lilly Doi获得旅行/会议费:10.1136/Annrheumdis-2022-Eular.2422016; 10:2217-28。[2] Suzuki M,Tse S,Hirai M,Kurebayashi Y.将基于生理的药代动力学建模应用于日语预测tofacitinib的预测。Kobe J Med Sci。 2017; 62(6):E150-E61。 Acknowledgements: Financial support was provided as an Investigator Spon- sored Research Grant from Pfizer Limited Disclosure of Interests: Stephanie Church Grant/research support from: Finan- cial support was provided as an Investigator Sponsored Research Grant from Pfizer Limited, Kimme Hyrich Speakers bureau: Honoraria as a speaker received from Abbvie, Grant/research support from: Financial support was provided as an Investigator Sponsored Research Grant from Pfizer 有限的。 AB在过去的12个月中获得了Scipher Medicine Ltd,Bristol Myers Squibb和Gal-Apagos的赠款。James Bluett Grant/Research Support in:Fanancial Support:Fanancial Support是作为调查员的PFISER LIM-IS提供的调查人员赞助研究赠款。 JB已从UCB,辉瑞和Eli Lilly Doi获得旅行/会议费:10.1136/Annrheumdis-2022-Eular.242Kobe J Med Sci。2017; 62(6):E150-E61。 Acknowledgements: Financial support was provided as an Investigator Spon- sored Research Grant from Pfizer Limited Disclosure of Interests: Stephanie Church Grant/research support from: Finan- cial support was provided as an Investigator Sponsored Research Grant from Pfizer Limited, Kimme Hyrich Speakers bureau: Honoraria as a speaker received from Abbvie, Grant/research support from: Financial support was provided as an Investigator Sponsored Research Grant from Pfizer 有限的。 AB在过去的12个月中获得了Scipher Medicine Ltd,Bristol Myers Squibb和Gal-Apagos的赠款。James Bluett Grant/Research Support in:Fanancial Support:Fanancial Support是作为调查员的PFISER LIM-IS提供的调查人员赞助研究赠款。 JB已从UCB,辉瑞和Eli Lilly Doi获得旅行/会议费:10.1136/Annrheumdis-2022-Eular.2422017; 62(6):E150-E61。Acknowledgements: Financial support was provided as an Investigator Spon- sored Research Grant from Pfizer Limited Disclosure of Interests: Stephanie Church Grant/research support from: Finan- cial support was provided as an Investigator Sponsored Research Grant from Pfizer Limited, Kimme Hyrich Speakers bureau: Honoraria as a speaker received from Abbvie, Grant/research support from: Financial support was provided as an Investigator Sponsored Research Grant from Pfizer 有限的。AB在过去的12个月中获得了Scipher Medicine Ltd,Bristol Myers Squibb和Gal-Apagos的赠款。James Bluett Grant/Research Support in:Fanancial Support:Fanancial Support是作为调查员的PFISER LIM-IS提供的调查人员赞助研究赠款。JB已从UCB,辉瑞和Eli Lilly Doi获得旅行/会议费:10.1136/Annrheumdis-2022-Eular.242Research grant award from BMS, Kayode Ogungbenro Consultant of: Afferent, Biogen, Buzzard, Grant/research support from: Financial support was provided as an Investi- gator Sponsored Research Grant from Pfizer Limited., Richard Unwin Grant/research support from: Financial support was provided as an Investigator Sponsored Research Grant from Pfizer Limited, Anne Barton Grant/research support from: Financial support was provided as an Investigator Sponsored Research Grant from Pfizer 有限的。