An iterative refinement model for PROTAC-induced structure prediction
这项工作被接受为 ICLR 2024 生物分子设计生成和实验视角研讨会的口头报告。有关更多信息,请查看我们在 arXiv 上的论文。什么是 PROTAC?蛋白质是分子机器,可执行人体生长所需的许多功能。当蛋白质发生故障时 […]
Making Standard Time Permanent Will Be Healthier For Americans: Study
Making Standard Time Permanent Will Be Healthier For Americans: StudyAuthored by Naveen Athrappully via The Epoch Times (emphasis ours),Adopting a permanent standard time in the United States rather than changing times biannually is a healthier option for Americans, according to a Sept. 15 peer-revi
上下文使凝块:蛇毒液凝血酶样酶诱导的纤维蛋白 - 凝胶凝胶形成在人与多样的动物质量质量植物之间形成的蛇形凝集蛋白 - 凝集静脉nake植物对猎物物种和人类咬伤受害者的血液化学产生动态影响。然而,比较测试以确定人与动物之间的差异性凝血毒性作用,因此,动物模型预测人类影响的适用性很少。为了填补这一知识差距,这项研究测试了用类似凝血酶的毒液在脊椎动物等离子体中起作用的pitviper,以及动物模型是否预测人类的结果。我们使用人类,啮齿动物,鸟类和两栖动物的血管造影,评估了Deinagkistrodon acutus,Gloydius tsushimaensis,Ovophis ovophis oxu
MiniMax Speech 2.5 Promises Real-Time AI Voices with Faster Speeds on GPT Proto Platform
完美综合演讲的竞赛刚刚起了数量。 Minimax已在GPT Proto AI平台上正式启动了Speech 2.5,吹捧针对需要即时,类似人类响应的企业和创作者的更快,更自然和实时的语音生成模型。对于上下文,此更新不仅仅是刮去毫秒的处理。这是关于使AI驱动的对话听起来不那么机器人,而是……嗯。根据该公司的说法,语音2.5具有高达60%的生成速度 - 这种升级对于诸如呼叫中心,虚拟助手或互动学习等实时场景很重要。坦率地说,任何曾经大喊的人[…]
Blood test to rule out oesophageal cancer
Proteomics International已在布里斯班的ISDE世界大会上推出了一项血液测试,以排除食道腺癌的血液测试(9月18日至20日)。该测试在澳大利亚设计和开发,为患有慢性反流(GORD)的人提供了快速,无创的内窥镜替代方案。食管癌(EAC)是最致命的癌症之一,巴雷特的食管(一种影响了多达2%的成年人的前体)通常无法诊断。 Promarkereso通过在初级保健环境中启用早期检测,改善及时诊断和治疗的访问,并确定目前可能错过的风险来解决这一关键差距。
Air India, IndiGo Launch Special Flights to Kathmandu After Violent Nepal Protests
Air India (AI) and IndiGo Airlines (6E) have begun operating special flights to Kathmandu, Nepal, to bring back stranded Indians after violent protests shut down Tribhuvan International Airport (KTM) for more than 24 hours.The post Air India, IndiGo Launch Special Flights to Kathmandu After Violent
Proteomic characterization and lethality of the venom of the Black Judean scorpion, Hottentotta judaicus (Buthidae): expanded toxin diversity and revisited toxicological significanceAbstractThe scorpion Hottentotta judaicus inhabits the Levant region of the Middle East, including Lebanon, Jordan, Pa
Why The Democrats' Latest Framework For Crypto Market Structure Could Hurt Financial Privacy
Why The Democrats' Latest Framework For Crypto Market Structure Could Hurt Financial PrivacyAuthored by Frank Corva via BitcoinMagazine.com,This morning, 12 Senate Democrats published a six-page framework for digital asset market structure legislation in which they outlined their plan to combat illi
'Skeptical' expert sounds alarm as Trump family launches new venture
过去,唐纳德·特朗普总统对加密货币高度批评。特朗普说,比特币是“基于稀薄的空气”,甚至指出它似乎是一个骗局。 But in 2025, Trump has a very different viewpoint, and his company Trump Media & Technology Group is quite bullish on cryptocurrencies.Financial journalist Dominic Basulto examines Trump's latest crypto venture in an article published by Nasdaq.
EPA is Turning a Blind Eye to Some of the Most Toxic Chemicals it Produces
“Advanced recycling” is a toxic scam — now the EPA is turning a blind eye to some of the most toxic chemicals it produces – Environment Defense Fund, EDF Health What’s new: Last month, the Environmental Protection Agency (EPA) withdrew a proposed rule covering 18 new chemicals, which would have paus
Губернатор штата Иллинойс прокомментировал возможный ввод минвойны Трампом в Чикаго
伊利诺伊州杰伊(Jay Protsker)的州长杰伊·普罗茨克(Jay Protsker)于9月6日称美国总统唐纳德·特朗普(Donald Trump)为“独裁者”,以回应芝加哥战争部士兵的可能进入,以打击移民。他在社交网络上写道:“美国总统威胁要与美国城市发动战争。
Optimizing MRO strategies for business aviation
当今的商业环境需要仔细审查MRO替代方案,以了解其对运营决策的收益,成本和影响。 Don van Dyke ATP/Helo/CFII,F28,Bell 222 Pro Protot Canada技术编辑Business Aircraft运营商和MROS经常共享相互依存的商业模式。前者依靠飞行小时,宪章费和管理合同,而[…]
DHS Terminates 2021 Temporary Protected Status For Venezuelans
dhs终止2021年,由雅各布·伯格(Jacob Burg)通过《时代》(Epoch Times)授权的临时保护状况,国土安全部(DHS)于9月3日宣布,它正在撤销2021年吊销2021年吊销临时部门的临时保护部门的临时保护部门,此前将于9月10日发布。通知联邦公报。 The department indicated that it no longer believes Venezuelan nationals met the statutory requirements for temporary protected status.“Given Venezuela’s substantial
LexisNexis Launches ‘Protégé In PatentSight+’
LexisNexis已启动其Genai驱动的专利+Protégé,它称其为“旗舰专利分析平台的直觉AI助手”,并且也是...
Other Transaction Agreements: Improved Contracting Data Would Help DOD Assess Effectiveness
GAO发现国防部(DOD)可以使用称为“其他交易协议”或OTA的合同机制来开发原型。 OTA不使用标准化的联邦收购条款和条件,而是依靠国防部签约官员来定制他们认为保护政府利益所必需的条款和条件。这种灵活性可能有助于国防部吸引非传统的国防承包商,否则可能不会选择与国防部签约。 However, this flexibility could also increase risk, such as by reducing oversight of contractors’ costs.After DOD successfully develops a prototype, it may produc
The CIA Vs DNI Tulsi Gabbard 'Cage-Match' Continues
中央情报局vs dni tulsi gabbard“笼子匹配”继续由“圣丹斯”(Sundance)通过最后一个避难所,如果您要阅读的内容有一个关键的收获,那就是这样。 Dni Tulsi Gabbard需要我们的支持。 DNI GABBARD正在深入的巨大孤岛系统中,该系统制造了孤立的幻觉,作为保护自身的策略。“没有什么比在引入新事物的新命令中领导的,更难以接管自己,更危险或更不确定其成功。” Tulsi Gabbard and her team need to hear, see and feel our support.Yesterday, the CIA Directorate of A
对亚马逊蝎子毒液的比较蛋白质组织和酶促分析可以使他们的第一个α-ktx,金属蛋白酶和磷脂酶A2ABSTRACTSCORPIONISM隔离,这是巴西的公共卫生越来越多,而亚马逊地区则呈现了最高的去世率,尤其是在本地构成的依据。 This study presents the first comprehensive biochemical characterization of venoms from three Amazonian species—Tityus metuendus (TmetuV), Tityus silvestris (TsilvV), and Brotheas amazoni