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Differentiating Small Enterprises in the Innovation Economy:
The recovery which followed in the 2010s was, in many ways, uneven and highly inequitable, with growth not being equitably distributed across sectors, communities or regions. With areas and people feeling ‘left behind' while others benefited from the recovery, this resulted in social, economic and political disruptions. If we wish the recovery of the 2020s to be more inclusive across a diverse set of actors, then we need to adopt an approach that is consciously inclusive and allows us to build back the entrepreneurial foundations of our economies in a different, more equitable way. An effective and inclusive approach to enterprise support requires that we attend to corner stores and ‘main street/high street' SME businesses, not just unicorns and high-tech start-ups. It requires an emphasis on productivity and employment, not simply revenue growth or valuation, and demands that we consider differentiation in support as well as coherence and simplification.
使用模型工作场所暴力预防计划的说明
同意议程项目日期：2024年7月26日至：邓普顿社区服务区董事会董事会，来自：Keri Dodson，执行助理/董事会职员主题：决议号17-2024 – Workplace Violence Prevention Program _____________________________________________________________________________ RECOMMENDED ACTION : That the Board of Directors, by motion, adopt Resolution No.17-2024采用了预防工作场所暴力计划。运动：________________/________________财政影响：无。背景：2023年9月，参议院第553号法案被签署为法律，要求加利福尼亚雇主采用一项工作场所暴力计划，以采取措施预防和应对工作场所的暴力行为。使用OSHA提供的模板，地区工作人员制定了一个在整个地区实施的预防工作场所暴力计划。每年制定计划时以及确定任何新的工作场所暴力危害时，将对计划进行培训。工作人员建议董事会采用决议号17-2024，采用附带的工作场所暴力计划。
莫桑比克运输案例研究-DV3 ...
3PL Third Party Logistics, a private transport supplier 4PL Fourth Party Logistics, a logistics firm that organises and contracts 3PL AAER Adopt, Adapt, Expand and Respond, a framework to analyse innovation scale-up BMGF Bill and Melinda Gates Foundation CBM Cost per Cubic Meter CHE Current Health Expenditure CHEGAR Commodities for Health Ensuring Guaranteed Access and Reliability CMAM Central Medical Stores COMSA Countrywide Mortality Surveillance for Action system FRELIMO The ruling party in government GDP Gross Domestic Product GPS Global Positioning System HIV Human Immunodeficiency Virus IMF International Monetary Fund LMSC Last Mile Supply Chain programme MISAU Ministry of Health NGO Non-Governmental Organisation PELF Strategic Plan for Pharmaceutical logistics PLM Project Last Mile RENAMO The opposition party in government SPS Provincial Health Departments UNFPA United Nations Population Fund UNICEF United Nations儿童基金美国国际发展局
8E-订单常规豁免 - 新泽西州
命令解决N.J.A.C.建立的某些要求的豁免14：8-10.3（d）案卷号。 QO19010068案卷号。 QX20030253记录派对：Stefanie A. Brand，Esq。，新泽西州董事会律师律师部董事：通过此顺序，董事会解决了实施过渡激励措施（“ TI”）规则1的规定，该规则1要求存在不可撤销的常规订单（“站立订单”（“站立订单”）之前，否则有资格的能源才能将其用作过渡可验证能量证书的基础。 BACKGROUND On May 23, 2018, the Clean Energy Act, L. 2018, c.17 (“Act”), was signed into law, and directed the Board to adopt rules and regulations to close the SREC Registration Program (“SRP”) to new registrations once 5.1% of the kilowatt-hours sold in the State are generated by solar electric power connected to the distribution system (known as the 5.1% Milestone), and continue the efficient and整个州的太阳能可再生能源的有序发展。 按日期为2019年12月6日的命令，董事会下令创建一个由固定价格和分解的TREC组成的过渡激励计划。 2通过日期为2020年1月8日的命令，董事会下令将TI计划继续向新注册开放，直到为当前正在开发的后继计划建立注册计划。 3在2020年4月6日，董事会确定5.1％的里程碑将是14：8-10.3（d）案卷号。QO19010068案卷号。QX20030253记录派对：Stefanie A.Brand，Esq。，新泽西州董事会律师律师部董事：通过此顺序，董事会解决了实施过渡激励措施（“ TI”）规则1的规定，该规则1要求存在不可撤销的常规订单（“站立订单”（“站立订单”）之前，否则有资格的能源才能将其用作过渡可验证能量证书的基础。 BACKGROUND On May 23, 2018, the Clean Energy Act, L. 2018, c.17 (“Act”), was signed into law, and directed the Board to adopt rules and regulations to close the SREC Registration Program (“SRP”) to new registrations once 5.1% of the kilowatt-hours sold in the State are generated by solar electric power connected to the distribution system (known as the 5.1% Milestone), and continue the efficient and整个州的太阳能可再生能源的有序发展。 按日期为2019年12月6日的命令，董事会下令创建一个由固定价格和分解的TREC组成的过渡激励计划。 2通过日期为2020年1月8日的命令，董事会下令将TI计划继续向新注册开放，直到为当前正在开发的后继计划建立注册计划。 3在2020年4月6日，董事会确定5.1％的里程碑将是Brand，Esq。，新泽西州董事会律师律师部董事：通过此顺序，董事会解决了实施过渡激励措施（“ TI”）规则1的规定，该规则1要求存在不可撤销的常规订单（“站立订单”（“站立订单”）之前，否则有资格的能源才能将其用作过渡可验证能量证书的基础。BACKGROUND On May 23, 2018, the Clean Energy Act, L. 2018, c.17 (“Act”), was signed into law, and directed the Board to adopt rules and regulations to close the SREC Registration Program (“SRP”) to new registrations once 5.1% of the kilowatt-hours sold in the State are generated by solar electric power connected to the distribution system (known as the 5.1% Milestone), and continue the efficient and整个州的太阳能可再生能源的有序发展。按日期为2019年12月6日的命令，董事会下令创建一个由固定价格和分解的TREC组成的过渡激励计划。2通过日期为2020年1月8日的命令，董事会下令将TI计划继续向新注册开放，直到为当前正在开发的后继计划建立注册计划。 3在2020年4月6日，董事会确定5.1％的里程碑将是2通过日期为2020年1月8日的命令，董事会下令将TI计划继续向新注册开放，直到为当前正在开发的后继计划建立注册计划。3在2020年4月6日，董事会确定5.1％的里程碑将是
通过抑制 P 糖蛋白介导的药物耐受持久细胞中有毒脂质过氧化副产物的清除，有效靶向治疗乳腺癌
Therapy resistance has long been considered to occur through the selection of pre-existing clones equipped to survive and quickly regrow, or through the acquisition of mutations during chemotherapy. Here we show that following in vitro treatment by chemotherapy, epithelial breast cancer cells adopt a transient drug tolerant phenotype characterized by cell cycle arrest, epithelial-to-mesenchymal transition (EMT) and the reversible upregulation of the multidrug resistance (MDR) efflux transporter P-glycoprotein (P-gp). The drug tolerant persister (DTP) state is reversible, as cells eventually resume proliferation, giving rise to a cell population resembling the initial, drug-naïve cell lines. However, recovery after doxorubicin treatment is almost completely eliminated when DTP cells are cultured in the presence of the P-gp inhibitor Tariquidar. Mechanistically, P-gp contributes to the survival of DTP cells by removing reactive oxygen species-induced lipid peroxidation products resulting from doxorubicin exposure. In vivo, prolonged administration of Tariquidar during doxorubicin treatment holidays resulted in a significant increase of the overall survival of Brca1 − / − ;p53 − / − mammary tumor bearing mice. These results indicate that prolonged administration of a P-gp inhibitor during drug holidays would likely benefit patients without the risk of aggravated side effects related to the concomitantly adminis tered toxic chemotherapy. Effective targeting of DTPs through the inhibition of P-glycoprotein may result in a paradigm shift, changing the focus from countering drug resistance mechanisms to preventing or delaying therapy resistance.
CalSTRS 的人工智能 -
• 创新者 – 第一批采用新技术的人。 • 早期采用者 – 早期采用者是意见领袖，他们在其领域备受尊重且知识渊博。 • 早期多数 – 比早期采用者更谨慎和持怀疑态度 • 晚期多数 – 仅在必要时采用 • 落后者 – 抵制新技术
沙特阿拉伯的可再生能源和创新
实现“净零”已成为世界各国政府关注的重点。要实现这一重大转变，必须激励公民个人采用“更清洁”的创新技术来减少碳足迹。在此背景下，我们的研究调查了可能鼓励或抑制沙特房屋消费者采用可再生能源（特别是太阳能光伏 (PV)）意愿的因素。借鉴计划行为理论，我们研究了人口变量与消费者对可再生能源 (RE) 的态度及其采用新 RE 技术的意愿之间的关系。我们的研究结果表明，消费者对 RE 缺乏了解是沙特消费者采用太阳能光伏的主要障碍。此外，消费者的环保信念可能不会直接导致采用 RE 的意愿，即使它与对该技术的有利态度有关。最后，社会影响力在推动沙特消费者采用 RE 时可能至关重要。这些是政策制定者在制定能源政策时需要注意和采取行动的重要考虑因素。
议程240730附件3.1.pdf
回顾社区愿景2021-2031。31/03/2025采用理事会计划2025-2029。31/03/2025采用评级和收入策略2025-2029。31/03/2025开发了2025/2026理事会预算，该预算在适当的情况下提供了公共价值并将股息退还给社区。预算将符合理事会的财务可持续性标准。