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Dexamethasone should be used only with extreme caution and frequent patient monitoring is necessary in patients with: diabetes mellitus or in those with a family history of diabetes, infectious diseases, congestive heart failure or recent myocardial infarction, chronic renal failure, liver failure, diverticulitis, hypertension, keratitis, epilepsy and/or seizure disorder, migraine, non-specific ulcerative colitis (if there is a probability of impending perforation, abscess or other pyogenic infection), fresh intestinal anastomoses, active or latent peptic ulcer, osteoporosis, myasthenia gravis receiving anticholinesterase therapy since corticosteroid use may decrease plasma anticholinesterase activity, or in elderly persons, geriatric patients may be more likely to develop hypertension and骨质疏松剂是皮质类固醇疗法，潜伏性的，因为皮质类固醇可能引起重新激活。在治疗之前，应在任何无法解释的腹泻的患者中排除敏病，或者最近在热带地区度过的时间。
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