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Received: 13-02-2025 / Revised Accepted: 13-02-2025 / Published: 15-02-2025 ABSTRACT: By using HPLC Remogliflozin and Teneligliptin was estimated by using a HSS C18 column of dimension 2.1 x 50mm, 1.8µm With KH2PO4 as buffer together with Acetonitrile in ratio of 40:60 at a flow of 0.2ml/min。在215 nm处检测到理想波长。在1.375分钟和1.736分钟时发现了teneligliptin和Remogliflozin的RT。系统Precision的RSD为1.2和0.6％。线性浓度在1.25-7.5 µg/ml的含素中观察到，对于十纤维蛋白，Remogliflozin为12.5-75 µg/ml。从获得的回归分别为y = 11748x + 329.21和y = 4428.9x + 4002.7。我们对所有其他因素的确认和观察是在定义的限制范围内确定的。关键词Remogliflozin，Teneligliptin，RP HPLC，验证，方法开发。
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