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干细胞系的替代名称1502.3（MCRII019-A）1502.3 COL2A1 p。G1170S（MCRII019-A-2）墨尔本默多克儿童研究所，澳大利亚墨尔本和马萨诸塞州科技研究所，美国美国技术研究所，分销商ShireenLamandéShireen.lamandéShireen.lamandé.lamande.lamande@mcri.edu.au; Associate Professor Matthew Shoulders mshoulde@mit.edu Type of cell lines iPSC Origin Human Cell Source Dermal fibroblast-derived human induced pluripotent cell line MCRIi019-A (http://hpscreg.eu/cell-line/MCRIi019-A) Clonality Clonal Method of reprogramming Episomal vectors Multiline rationale Isogenic clones Gene modification Yes Type of modification Induced mutation Associated disease Legg-Calve-Perthes Disease OMIM #150600 Gene/locus COL2A1 c.3508 GGT > TCA (p.G1170S) Chromosome 12q13.11 Method of modification CRISPR/Cas9 Name of transgene or resistance N/A Inducible/constitutive system N/A Date archived/stock date February 2019 Cell line repository/bank https://hpscreg.eu/cell-line/mcrii019-a; https://hpscreg.eu/cell-line/mcrii019-a-2伦理批准这项研究得到了皇家儿童医院（HREC 33118）的人类研究伦理委员会的批准，澳大利亚维多利亚州
干细胞研究
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