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• Obtain an ECG prior to dosing, and at the end of the 6-hour observation period • Monitor patients for signs and symptoms of bradycardia, with hourly pulse and blood pressure measurements • If symptoms of bradyarrhythmia or atrioventricular (AV) block occur, initiate appropriate management, with continuous monitoring (e.g.连续的心电图监测）直到症状解决。•患者应在一剂量观察期间需要药理干预，连续过夜监测（例如连续的ECG监测）应在医疗设施中建立，并在管理第二剂量的Ozanimod时重复第一剂量监测策略。
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