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g支持性护理和治疗修饰考虑iMID所需的血栓预防(例如,列纳利度胺,Pomalidomide);选项包括阿司匹林,依诺肝素或DOAC; DOAC首选与蛋白质体抑制剂(例如Bortezomib,Carfilzomib)以及CD38抗体(例如Daratumumab)(例如Daratumab)PJPProghaxis Proghaxis Pssuned Puspeans dex Ade dex Adex Adex Adex Adex Adex Adex Adex Adex Adex preconce dex Adex Adex precons dex Adexs precons/dex precsights dex precsights dex hys/pjp Proghaxis proghandspepsions dex nefe nime是较高的血栓形成风险。 Lenalidomide requires dose reduction/modification based on renal function  Dexamethasone should be dose reduced to 20 mg weekly for age >75 years  Once multiple myeloma response has been reached, dexamethasone dosing frequency should be reduced or even discontinued to reduce risk of infections  Bortezomib should be administered subcutaneously to reduce risk of neuropathy.Consider weekly bortezomib administration to reduce risk of neuropathy  Subcutaneous daratumumab is preferred over daratumumab due to reduced adverse reactions and faster administration  T&S and antibody screen and hepatitis B serologies prior to daratumumab or daratumumab administration  Palliative XRT for painful osseous lesions;在移植候选者的患者中,最大程度地减少骨髓暴露,尤其是骨盆的暴露考虑未参与免疫球蛋白和复发性感染的降低症患者的IVIG

肿瘤学临床途径 - 浆细胞疾病

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