g支持性护理和治疗修饰考虑iMID所需的血栓预防(例如,列纳利度胺,Pomalidomide);选项包括阿司匹林,依诺肝素或DOAC; DOAC首选与蛋白质体抑制剂(例如Bortezomib,Carfilzomib)以及CD38抗体(例如Daratumumab)(例如Daratumab)PJPProghaxis Proghaxis Pssuned Puspeans dex Ade dex Adex Adex Adex Adex Adex Adex Adex Adex Adex preconce dex Adex Adex precons dex Adexs precons/dex precsights dex precsights dex hys/pjp Proghaxis proghandspepsions dex nefe nime是较高的血栓形成风险。 Lenalidomide requires dose reduction/modification based on renal function Dexamethasone should be dose reduced to 20 mg weekly for age >75 years Once multiple myeloma response has been reached, dexamethasone dosing frequency should be reduced or even discontinued to reduce risk of infections Bortezomib should be administered subcutaneously to reduce risk of neuropathy.Consider weekly bortezomib administration to reduce risk of neuropathy Subcutaneous daratumumab is preferred over daratumumab due to reduced adverse reactions and faster administration T&S and antibody screen and hepatitis B serologies prior to daratumumab or daratumumab administration Palliative XRT for painful osseous lesions;在移植候选者的患者中,最大程度地减少骨髓暴露,尤其是骨盆的暴露考虑未参与免疫球蛋白和复发性感染的降低症患者的IVIG
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