a Diagnosis must include flow cytometry, karyotype, rapid order (<72 hours) molecular tests (to include: FLT3, NPM1, IDH1, and IDH2), and myeloid NGS test (at minimum must include: ASXL1, BCOR, CEBPA, EZH2, FLT3, IDH1, IDH2, NPM1, RUNX1, SF3B1, srsf2,stag2,tp53,u2af1和zrsr2);其他可选基因包括:CBL,DDX41,KIT,KRAS,NRA和其他与髓样肿瘤相关的基因;也可以在病理学家的前提下或自行决定进行AML鱼类测试(可以包括:-5/5Q,-7/7Q,-7/7Q,KMT2A,T(8; 21)runx1 :: Runx1t1,t(15; 17; 17)PML :: Rara,t(16:16)或Inv(16:16)或Inv(16)或Inv(16)CBFB :: bbfb :: bbl :: bbl:n; TP53)