•用于利用平行多词数据的统计方法将上游信号通路的失调与转录反应的改变联系起来(Osmanbeyoglu等人,基因组研究,2014年)•PAN-CANCER分析确定了突变对TF和(Phospho)蛋白质活性的影响(OSMANBEYOGLU ETICICTICATIC ENCORICTION,PSICINIC,2017),2017年。染色质),一种多任务回归框架,可预测染色质访问元件中转录因子(TF)结合基序的患者特异性基因表达谱。(Osmanbeyoglu# et al., Nature Communications , 2019 ) (#=co-corresponding authors) • CITRUS (C hromatin-informed I nference of T ranscriptional R egulators U sing S elf-attention mechanism), a partially interpretable neural network (NN) model with encoder-decoder architecture to link somatic alterations to transcriptional programs (Tao*, Ma* et al.,核酸研究,2022年)(对应作者)
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