XiaoMi-AI文件搜索系统
World File Search Systemproportion
nt健康战略计划2023-2028
具有积极经验精神健康支持和服务率的患者和护理人的比例，可能预防的住院和慢性病率（包括肥胖症，2型糖尿病，慢性肾脏疾病和心血管疾病）的比例，人口吸烟，消费饮酒，饮酒，饮酒，饮食和健康饮食率的健康状况/养生率的健康饮食率和生活率的健康状况的比例（医院分离的出生率和受伤的入院率
CADTH Reimbursement Recommendation
One double-blind, phase 2/3, randomized controlled trial (RCT) (N-MOmentum, N = 230) in patients with NMOSD demonstrated that, among AQP4 seropositive patients (N = 213) treatment with inebilizumab likely results in a clinically meaningful increase in time to first relapse and a reduction in the proportion of patients with worsening in Expanded Disability Status Scale (EDSS) compared to treatment with placebo after 197 days of treatment. Among AQP4 seropositive patients, the hazard ratio (HR) for time to first Adjudication Committee (AC)–determined NMOSD attack was 0.28 (95% confidence interval [CI]: 0.12 to 0.42, P < 0.0001) and at day 197, 87.6% of patients in the inebilizumab group were attack-free compared to 56.6% in the placebo group, which equated to a 77.3% reduction in the risk of AC-determined NMOSD attack. The CADTH review of the sponsor's submitted indirect treatment comparisons concluded that inebilizumab did not offer a benefit relative to eculizumab, and that imprecision in the estimated HR prevented a definitive conclusion from being reached in the comparison with satralizumab.
免疫检查点抑制剂在转移性胰腺癌中的作用：当前状态和Outlook
摘要：胰腺导管腺癌（PDAC）是最致命的肿瘤之一，其特征是其侵略性肿瘤生物学和预后不良。虽然免疫检查点抑制剂（ICI）在各种实体瘤的治疗算法中起主要作用，但对于转移性PDAC（MPDAC）患者，ICI仍然没有证据表明ICI临床受益。This might be due to several reasons, such as the inherent low immunogenicity of pancreatic cancer, the dense stroma-rich tumor microenvironment that precludes an efficient migration of antitumoral effector T cells to the cancer cells, and the increased proportion of immunosuppressive immune cells, such as regulatory T cells (Tregs), cancer-associated fibroblasts （CAF）和粒细胞来源的抑制细胞（MDSC），促进肿瘤的生长和侵袭。在这篇综述中，我们提供了MPDAC中ICI当前状态的概述，报告了将ICIS实施胰腺癌治疗策略的生物学原理报告，并讨论了该领域的临床前研究和临床试验。此外，我们阐明了将ICIS实施到PDAC的治疗策略中的挑战，并讨论了潜在的未来方向。
教学大纲 - 辅助技术 - 实验室 -
那些在纸上获得最低资格标记的候选人。GENERAL APTITUDE Paper I (Part I – MCQs – 25 marks) General Knowledge: Indian History, Indian Geography, Indian Economy, Indian Polity & Constitution, Current Affairs-India & World, Current Events, Reasoning Ability: Analogies – Semantic Analogy, Symbolic / Number Analogy, Figural Analogy, Similarities & Differences, Word building, Relationship concepts, Arithmetic Number series – Semantic Series, Number Series, Coding & decoding – Small & Capital letters/ numbers编码，解码和分类。Numerical Ability: Number System, Time & Work, Averages, Percentages, Profit & Loss, Ratio & Proportion, Simple & Compound Interest, Time & Distance General English: Comprehension, One-word substitution, Synonyms & Antonyms, Spelling error, spotting error in sentences, Grammar- Noun, Pronoun, Adjective, Verb, Preposition, Conjunction, Use of ‘A', ‘AN' & ‘The', Idioms &短语，语言水平。域知识纸-I（第二部分 - MCQS-75分数）
精选作品和持续调查评分标准
2-D Art and Design Skills: the application of two-dimensional elements and principles—point, line, shape, plane, layer, form, space, texture, color, value, opacity, transparency, time; unity, variety, rhythm, movement, proportion, scale, balance, emphasis, contrast, repetition, figure/ground relationship, connection, juxtaposition, hierarchy 3-D Art and Design Skills: the application of three-dimensional elements and principles—point, line, shape, plane, layer, form, volume, mass, occupied/unoccupied space, texture, color, value, opacity, transparency, time; unity, variety, rhythm, movement, proportion, scale, balance, emphasis, contrast, repetition, connection, juxtaposition, hierarchy Advanced: highly developed Demonstrate: to clearly show Describe: using words to communicate relevant information Development: the furthering or advancing of an inquiry in a sustained investigation (through in-depth exploration of materials, processes, and ideas) Discovery: to learn something through the process of making Drawing Skills: the application of mark-making, line, surface, space, light and shade, composition Experimentation: testing materials, processes, and/or ideas Exploration: a journey of experimentation and discovery directed by inquiry Evidence: to make obvious, seen, or understood Good : proficient Guides: the i nquiry leads the process of making works of art and design Ideas: concepts used to make works of works art and design (evident visually or in writing) Identify: indicate or provide information Inquiry: the intentional process of questioning to guide exploration and discovery over time Intent: the purpose or reason for exploring an idea Materials: physical substances used to make works of art and design Moderate : adequate Practice: the repeated use of materials, processes, and/or ideas Processes: physical and conceptual activities including applications involved with making works of art and design Questioning: purposeful investigation and discovery in relationship to an idea Reimagine: reinterpret with imagination; rethink Relate: having a relationship and/or connection between Revision : to modify, clarify, or reimagine works and ideas Rudimentary : emerging or undeveloped Sustained Investigation: an inquiry-based and in-depth study of materials, processes, and ideas over time Synthesis: coalescence/integration of materials, processes, and ideas Visual Evidence: the visual components that make up the student's works of art and design Visual Relationships: connections between the visual components included in a student's works of art and design Ways: a series of actions or events leading in a direction or toward an objective Written Evidence: the written components that accompany the student's works of art and design
学期 - III英语-III（沟通技巧）学分：3
应用程序。比率，直接比例，逆比例及其相关问题。功能线性函数：线性方程的应用，求解线性方程的系统。图形工具及其在不同学科中的应用程序。一个变量中的代数表达式，线性和二次方程式，它们在
danicopan（Voydeya）
一项随机对照试验（RCT）（alpha; 12周的安慰剂对照期[TP1]加上为期12周的单臂开放标签期[TP2]和52周的长期长期延长[LTE]）与Danicopan相比，Danicopan与临床上具有临床意义的EVH的C5I患者中的Danicopan与bactopan bact。TP1的结果表明，在没有输血的情况下，血红蛋白增加2G/DL或更多的血红蛋白增加2G/DL的患者的比例有所改善。该试验对HRQOL的影响的证据表明，疲劳的改善（慢性病的功能评估[FACIT] -FATIGUE）得分很少，而HRQOL，EQ-5D-3L的其他2次衡量标准则几乎没有差异，EQ-5D-3L和欧洲的欧洲组织研究和治疗组织的癌症质量质量调查员核核心30 [Eortc Q Qlq-Qlq-Qlq-q-Clq-c-Clq-clq-cle Qulq-Q Qlq-q clq-q clq clq-c 30]TP2的结果表明，维持对血液学结局的影响，对HRQOL的影响提出了维持得分的趋势。完整分析的结果表明，在LTE中，TP2的报告趋势是多种血液学结局的（血红蛋白归一化的患者比例，血红蛋白增加2G/DL或更高的患者比例增加了2G/DL或更高，基础血红蛋白的变化）。
AI时代的性别能量Nexus
5.1.1 Whether or not legal frameworks are in place to promote, enforce and monitor equality and non‑discrimination on the basis of sex 5.2 Eliminate all forms of violence against all women and girls in the public and private spheres, including trafficking and sexual and other types of exploitation 5.2.1 Proportion of ever-partnered women and girls aged 15 years and older subjected to physical, sexual or psychological violence by a current or former intimate partner in the previous 12个月，按暴力形式和按年龄为5.2.2年龄在15岁及以上的妇女和女孩的比例在前12个月以外的其他人进行性暴力，在过去的12个月中，按照年龄和发生的地点为止，以5.3的年龄和地点消除了所有有害行为，消除了所有有害习俗，例如儿童，早期和强迫婚姻和强迫婚姻和女性施加妇女的年龄5.3.1妇女的年龄5.3.1岁以前的女性及其年龄的年龄。通过提供公共服务，基础设施和社会保护政策以及家庭内部的共同责任和家庭在全国范围内促进共同的责任5.4.1在全国范围内促进5.4.1的时间比例为5.4.1，在5.4.1的家庭中花费了5.4.1在无偿的家庭和保健工作，按性别，年龄，年龄，年龄，年龄，年龄，
casgevy™（exagamglogene autotemcel） - 新孤儿...
•CASGEVY还获得批准用于治疗12岁及以上患有镰状细胞疾病（SCD）的患者，患有经常性的血管结构危机。•Casgevy是第二种基于细胞的基因疗法，获得了TDT的批准。Bluebird Bio'sZynteglo®（Betibeglogene autotemcel）于2022年8月批准了成人和小儿TDT患者的治疗。•casgevy批准新指标是基于对TDT的成人和青少年患者进行的持续开放标签，单臂研究。合格的患者接受了动员和分离术以收集CD34+干细胞进行Casgevy生产，然后进行骨髓性调理和casgevy的输注。35例患者有足够的随访，以评估初级疗效终点并形成主要疗效集（PES）。The primary outcome was the proportion of patients achieving transfusion independence for 12 consecutive months (TI12), defined as maintaining weighted average Hb ≥ 9 g/dL without red blood cell (RBC) transfusions for at least 12 consecutive months any time within the first 24 months after Casgevy infusion, evaluated starting 60 days after the last RBC transfusion for post- transplant support or TDT disease management.