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• Demographic predictors • Age, sex, ethnicity and race, socioeconomic status • Behavioral and Lifestyle Predictors • Sleep quality, physical activity, smoking status, medication adherence, substance use • Social and Environmental Predictors • Social support, work-related factors, environmental stressors, healthcare access • Psychological predictors • Anxiety, depression, fear-avoidance beliefs, pain catastrophizing, self-efficacy • Trait, state, evoked •患者报告的结果指标（PROS或PROMS）
整合生物标志物和预测因子以提高精度疼痛管理
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