umbrella study to investigate tolerability, Pk, and antitumor activity of ARV-471 (PF- 07850327), an oral proteolysis targeting chimera, in combination with other anticancer treatments in participants aged 18 years and over with ER+ advanced or metastatic breast cancer, sub-study a (ARV-471 in combination with Abemaciclib) PI: Rachel Layman SM: Lamiae Sahnoune(lsahnoune@mdanderson.org,713-792-7173)g。 2023-0130:Tactive-U:介入的安全性和功效阶段1b/2,开放标签
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